Virus infections usually begin in peripheral tissues and can invade the mammalian nervous
system (NS), spreading into the peripheral (PNS) and more rarely the central (CNS) nervous …

Enterovirus-induced infection of the central nervous system (CNS) results in acute
inflammation of the brain (encephalitis) and constitutes a significant global burden to human …

Enteroviruses (EV) frequently infect the central nervous system (CNS) and induce
neurological diseases. Although the CNS is composed of many different cell types, the …

CNS infections continue to rise in incidence in conjunction with increases in
immunocompromised populations or conditions that contribute to the emergence of …

The striking differences between the clinical symptoms of tetanus and botulism have been
ascribed to the different fate of the parental neurotoxins once internalised in motor neurons …

To reach the central nervous system (CNS), pathogens have to circumvent the wall of tightly
sealed endothelial cells that compose the blood–brain barrier. Neuronal projections that …

Flaviviruses are present on every continent and cause significant morbidity and mortality. In
many instances, severe cases of infection with flaviviruses involve the invasion of and …

Genetic recombination in RNA viruses was discovered many years ago for poliovirus (PV),
an enterovirus of the Picornaviridae family, and studied using PV or other picornaviruses as …

Abstract Purpose of Review The focus of this review is on enterovirus (EV)-associated acute
flaccid paralysis (AFP) due to spinal cord anterior horn cell disease. Emphasis is placed on …

Abstract Tetanus (TeNT) and botulinum (BoNT) neurotoxins, the causative agents of tetanus
and botulism, respectively, are the most potent toxic molecules known to mankind. This …