Bone turnover markers (BTMs) are used widely, in both research and clinical practice. In the
last 20 years, much experience has been gained in measurement and interpretation of these …

Clinical practice guidelines recommend an arteriovenous fistula as the preferred vascular
access for hemodialysis, but quantitative associations between vascular access type and …

Context Clinical practice guidelines on the management of mineral and bone disorders due
to chronic kidney disease recommend specific treatment target levels for serum phosphorus …

Bicarbonate supplementation preserves renal function in experimental chronic kidney
disease (CKD), but whether the same benefit occurs in humans is unknown. Here, we …

Alkaline phosphatase (ALP) is an evolutionary conserved enzyme and widely used
biomarker in clinical practice. Tissue-nonspecific alkaline phosphatase (TNALP) is one of …

This issue provides a clinical overview of chronic kidney disease, focusing on prevention,
diagnosis, treatment, and patient information. The content of In the Clinic is drawn from the …

Atualmente, é amplamente aceita a definição da doença renal crônica (DRC) que se baseia
em alterações na taxa de filtração glomerular e/ou presença de lesão parenquimatosa …

Objectives Vitamin D insufficiency has been linked to hypertension and cardiovascular
events in observational studies. It is unclear whether vitamin D supplementation can reduce …

Vitamin D seems to protect against cardiovascular disease, but the reported effects of
vitamin D on patient outcomes in CKD are controversial. We conducted a prospective …

Background: Patients with chronic kidney disease (CKD) are at increased risk for kidney
failure, cardiovascular events, and all-cause mortality. Accurate models are needed to …