Learning without neurons in physical systems

M Stern, A Murugan - Annual Review of Condensed Matter …, 2023 - annualreviews.org
Learning is traditionally studied in biological or computational systems. The power of
learning frameworks in solving hard inverse problems provides an appealing case for the …

Disordered mechanical metamaterials

M Zaiser, S Zapperi - Nature Reviews Physics, 2023 - nature.com
Mechanical metamaterials are a class of artificial materials whose geometry is engineered to
have peculiar mechanical properties or programmed responses that are difficult to find in …

Allostery in its many disguises: from theory to applications

SJ Wodak, E Paci, NV Dokholyan, IN Berezovsky… - Structure, 2019 - cell.com
Allosteric regulation plays an important role in many biological processes, such as signal
transduction, transcriptional regulation, and metabolism. Allostery is rooted in the …

Learning to learn by using nonequilibrium training protocols for adaptable materials

MJ Falk, J Wu, A Matthews… - Proceedings of the …, 2023 - National Acad Sciences
Evolution in time-varying environments naturally leads to adaptable biological systems that
can easily switch functionalities. Advances in the synthesis of environmentally responsive …

From jammed solids to mechanical metamaterials: A brief review

J Huang, J Zhang, D Xu, S Zhang, H Tong… - Current Opinion in Solid …, 2023 - Elsevier
Here we review recent studies of mechanical metamaterials originating from or closely
related to marginally jammed solids. Unlike previous approaches mainly focusing on the …

Physical effects of learning

M Stern, AJ Liu, V Balasubramanian - Physical Review E, 2024 - APS
Interacting many-body physical systems ranging from neural networks in the brain to folding
proteins to self-modifying electrical circuits can learn to perform diverse tasks. This learning …

Allosteric type and pathways are governed by the forces of protein–ligand binding

Q Huang, P Song, Y Chen, Z Liu… - The Journal of Physical …, 2021 - ACS Publications
Allostery is central to many cellular processes, by up-or down-regulating target function.
However, what determines the allosteric type remains elusive and currently it is impossible …

Exploring the allosteric territory of protein function

WV Tee, ZW Tan, K Lee, E Guarnera… - The journal of physical …, 2021 - ACS Publications
While the pervasiveness of allostery in proteins is commonly accepted, we further show the
generic nature of allosteric mechanisms by analyzing here transmembrane ion-channel …

Digital strategies for structured and architected materials design

S Bonfanti, R Guerra, M Zaiser, S Zapperi - APL Materials, 2021 - pubs.aip.org
Designing materials with tailored structural or functional properties is a fundamental goal of
materials science and engineering. A vast research activity is currently devoted to achieving …

Automatic design of mechanical metamaterial actuators

S Bonfanti, R Guerra, F Font-Clos… - Nature …, 2020 - nature.com
Mechanical metamaterial actuators achieve pre-determined input–output operations
exploiting architectural features encoded within a single 3D printed element, thus removing …