Background X‐linked ichthyosis (XLI) is a rare genetic condition almostexclusively affecting
males; it is characterised by abnormal desquamation and retentionhyperkeratosis, and …

Fibrosis is characterized by excessive matrix protein accumulation and contributes to
significant morbidity and mortality in the Western world. The relative lack of effective …

Background Ever since the classification of Dupuytren disease into the proliferative,
involutional, and residual stages, extensive research has been performed to uncover the …

Development of an ideal biomaterial for clinical use is one of the main objectives of current
research in tissue engineering. Marine-origin polysaccharides, in particular agaroses, have …

The generation of elastic cartilage substitutes for clinical use is still a challenge. In this study,
we investigated the possibility of encapsulating human elastic cartilage-derived …

Mesenchymal stem cells (MSCs) can differentiate toward epithelial cells and may be used
as an alternative source for generation of heterotypical artificial human skin substitutes, thus …

A previously developed fibrin‐agarose skin model—UGRSKIN—showed promising clinical
results in severely burnt patients. To determine the histological parameters associated to the …

Five agarose types (D1LE, D2LE, LM, MS8 and D5) were evaluated in tissue engineering
and compared for the first time using an array of analysis methods. Acellular and cellular …

Congenital clubfoot is a complex musculoskeletal deformity, in which a stiff, contracted
tissue forms in the medial part of the foot. Fibrotic changes are associated with increased …

Dupuytren's disease is a chronic, progressive fibroproliferative condition of the hand fascia
which results in digital contraction. So far, treatments do not directly interfere with the (myo) …