Candida Infections and Therapeutic Strategies: Mechanisms of Action for Traditional and Alternative Agents
GC de Oliveira Santos, CC Vasconcelos… - Frontiers in …, 2018 - frontiersin.org
The Candida genus comprises opportunistic fungi that can become pathogenic when the
immune system of the host fails. Candida albicans is the most important and prevalent …
immune system of the host fails. Candida albicans is the most important and prevalent …
Antifungals discovery: an insight into new strategies to combat antifungal resistance
AM Fuentefria, B Pippi, DF Dalla Lana… - Letters in applied …, 2018 - academic.oup.com
Undeniably, new antifungal treatments are necessary against pathogenic fungi. Fungal
infections have significantly increased in recent decades, being highlighted as important …
infections have significantly increased in recent decades, being highlighted as important …
Impact of novel microbial secondary metabolites on the pharma industry
D Ramírez-Rendon, AK Passari, B Ruiz-Villafán… - Applied Microbiology …, 2022 - Springer
Microorganisms are remarkable producers of a wide diversity of natural products that
significantly improve human health and well-being. Currently, these natural products …
significantly improve human health and well-being. Currently, these natural products …
Synergistic combinations of antifungals and anti-virulence agents to fight against Candida albicans
Candida albicans, one of the pathogenic Candida species, causes high mortality rate in
immunocompromised and high-risk surgical patients. In the last decade, only one new class …
immunocompromised and high-risk surgical patients. In the last decade, only one new class …
Antifungal Combinations against Candida Species: From Bench to Bedside
Candida spp. is the major causative agent of fungal infections in hospitalized patients and
the fourth most common cause of nosocomial bloodstream infection (BSI). The availability of …
the fourth most common cause of nosocomial bloodstream infection (BSI). The availability of …
Prevention of tumor risk associated with the reprogramming of human pluripotent stem cells
K Wuputra, CC Ku, DC Wu, YC Lin, S Saito… - Journal of Experimental …, 2020 - Springer
Human pluripotent embryonic stem cells have two special features: self-renewal and
pluripotency. It is important to understand the properties of pluripotent stem cells and …
pluripotency. It is important to understand the properties of pluripotent stem cells and …
Synergistic interactions of sulfamethoxazole and azole antifungal drugs against emerging multidrug-resistant Candida auris
HE Eldesouky, X Li, NS Abutaleb, H Mohammad… - International journal of …, 2018 - Elsevier
Candida auris is an emerging multidrug-resistant pathogen implicated in numerous
outbreaks worldwide, with a notably high mortality rate (ca. 60%). A significant challenge …
outbreaks worldwide, with a notably high mortality rate (ca. 60%). A significant challenge …
Candida albicans Heat Shock Proteins and Hsps-Associated Signaling Pathways as Potential Antifungal Targets
Y Gong, T Li, C Yu, S Sun - Frontiers in cellular and infection …, 2017 - frontiersin.org
In recent decades, the incidence of invasive fungal infections has increased notably.
Candida albicans (C. albicans), a common opportunistic fungal pathogen that dwells on …
Candida albicans (C. albicans), a common opportunistic fungal pathogen that dwells on …
Antimicrobial Peptides: Avant-Garde Antifungal Agents to Fight against Medically Important Candida Species
GP Rodríguez-Castaño, F Rosenau, L Ständker… - Pharmaceutics, 2023 - mdpi.com
Expanding the antifungal drug arsenal for treating Candida infections is crucial in this era of
the rising life expectancy of patients with immunosuppression and comorbidities. Infections …
the rising life expectancy of patients with immunosuppression and comorbidities. Infections …
Potent synergistic interactions between lopinavir and azole antifungal drugs against emerging multidrug-resistant Candida auris
The limited therapeutic options and the recent emergence of multidrug-resistant Candida
species present a significant challenge to human medicine and underscore the need for …
species present a significant challenge to human medicine and underscore the need for …