Liver cancer is the fifth most common cancer and the second most frequent cause of cancer-
related death globally. Hepatocellular carcinoma represents about 90% of primary liver …

Studies in the last decade have suggested the association of both neuroinflammatory
processes and immune responses in Parkinson disease (PD) pathology. PD pathology is …

Pain is a very frequent symptom with influence on the quality of life in Parkinson's disease
(PD), but is still underdiagnosed and commonly treated only unsystematically. Pain etiology …

Background Pain is a common non-motor symptom of Parkinson's disease. We investigated
the analgesic efficacy of prolonged-release oxycodone–naloxone (OXN PR) in patients with …

Pain in Parkinson's disease is not simply a consequence of motor complainants. The
management of Parkinson's disease-related pain implicates maintenance of stable levels of …

Pain is one of the most common and troublesome non‐motor symptoms of Parkinson's
disease (PD). It can appear at any time during the disease and is often present before …

Pain is a troublesome nonmotor symptom of Parkinson's disease (PD). This double‐blind
exploratory pilot study (NCT01744496) was the first to specifically investigate the effect of a …

Nonmotor manifestations in Parkinson's disease (PD) encompass a range of clinical
features, including neuropsychiatric problems, autonomic dysfunction, sleep disorders …

Pain is a commonly occurring non-motor symptom of Parkinson's disease (PD). Treatment of
pain in PD remains less than optimal and a better understanding of the underlying …

Parkinson's disease is primarily caused by dysfunction of dopaminergic neurons, however,
nondopaminergic (ND) systems are also involved. ND targets are potentially useful to …