Calcific aortic valve disease (CAVD) is the most common disorder affecting heart valves and
is characterized by thickening, fibrosis and mineralization of the aortic valve leaflets …

Autogenous odontogenic materials are a new, highly biocompatible option for jaw
restoration. The inorganic component of autogenous teeth acts as a scaffold to maintain the …

Bioactive piezoelectric materials with similar properties as natural bone tissue with
piezoelectricity have been explored for bone repair. Polyvinylidene fluoride (PVDF) is …

Background Mesenchymal stem cell (MSC)-based tissue engineering plays a major role in
regenerative medicine. However, the efficiency of MSC transplantation and survival of …

Long-term nonunion of bone defects has always been a major problem in orthopedic
treatment. Artificial bone graft materials such as Poly (lactic-co-glycolic acid)/β-tricalcium …

Abstract Three-dimensional (3D) printing technology is driving forward the progresses of
various engineering fields, including tissue engineering. However, the pristine 3D-printed …

Runt-related transcription factor 2 (RUNX2) is an osteogenesis-related transcription factor
that has emerged as a prominent transcription repressing factor in carcinogenesis. However …

Heterotopic ossification (HO) is defined as the occurrence of extraskeletal bone in soft
tissue. Although this pathological osteogenesis process involves the participation of …

Emerging evidence supports that osteogenic differentiation of skeletal progenitors is a key
determinant of overall bone formation and bone mass. Despite extensive studies showing …

Osteoporosis occurs due to a dysregulation in bone remodeling, a process requiring both
bone-forming osteoblasts and bone-resorbing osteoclasts. Current leading osteoporosis …