[HTML][HTML] Mitochondria as potential targets in Alzheimer disease therapy: an update

G Cenini, W Voos - Frontiers in pharmacology, 2019 - frontiersin.org
Alzheimer disease (AD) is a progressive and deleterious neurodegenerative disorder that
affects mostly the elderly population. At the moment, no effective treatments are available in …

Vitamin E therapy beyond cancer: Tocopherol versus tocotrienol

HY Peh, WSD Tan, W Liao, WSF Wong - Pharmacology & therapeutics, 2016 - Elsevier
The discovery of vitamin E (α-tocopherol) began in 1922 as a vital component required in
reproduction. Today, there are eight naturally occurring vitamin E isoforms, namely α-, β-, γ …

[HTML][HTML] Mitochondrial dysfunctions: a red thread across neurodegenerative diseases

S Stanga, A Caretto, M Boido, A Vercelli - International journal of …, 2020 - mdpi.com
Mitochondria play a central role in a plethora of processes related to the maintenance of
cellular homeostasis and genomic integrity. They contribute to preserving the optimal …

[HTML][HTML] Potential role of tocotrienols on non-communicable diseases: a review of current evidence

SK Wong, Y Kamisah, N Mohamed, N Muhammad… - Nutrients, 2020 - mdpi.com
Tocotrienol (T3) is a subfamily of vitamin E known for its wide array of medicinal properties.
This review aimed to summarize the health benefits of T3, particularly in prevention or …

[HTML][HTML] Targeting mitochondrial bioenergetics as a promising therapeutic strategy in metabolic and neurodegenerative diseases

GK Bhatti, A Gupta, P Pahwa, N Khullar, S Singh… - biomedical …, 2022 - Elsevier
Mitochondria are the organelles that generate energy for the cells and act as biosynthetic
and bioenergetic factories, vital for normal cell functioning and human health. Mitochondrial …

Impact of micronutrients and nutraceuticals on cognitive function and performance in Alzheimer's disease

L Guarnieri, F Bosco, A Leo, R Citraro, E Palma… - Ageing Research …, 2024 - Elsevier
Alzheimer's disease (AD) is a major global health problem today and is the most common
form of dementia. AD is characterized by the formation of β-amyloid (Aβ) plaques and …

Nutritional Interventions for the Prevention of Neurodegenerative Disorders

P Banerjee, S Maitra, P Bhadra, A Das… - … and Functional Foods …, 2021 - taylorfrancis.com
Nutrition plays an important role in maintaining the normal physiological functions of human
body. Healthy food habit and balanced lifestyle can reduce the risk of several diseases …

[HTML][HTML] Are vitamin e supplementation beneficial for female gynaecology health and diseases?

NA Md Amin, SH Sheikh Abdul Kadir, AH Arshad… - Molecules, 2022 - mdpi.com
Vitamin E is known as an essential vitamin, and many studies had demonstrated the
importance of vitamin E throughout the reproductive process, such as miscarriage …

[HTML][HTML] Apoptosis and compensatory proliferation signaling are coupled by CrkI-containing microvesicles

KH Gupta, JW Goldufsky, SJ Wood, NJ Tardi… - Developmental cell, 2017 - cell.com
Apoptosis has been implicated in compensatory proliferation signaling (CPS), whereby
dying cells induce proliferation in neighboring cells as a means to restore homeostasis. The …

[HTML][HTML] Safety and neuroprotective efficacy of palm oil and tocotrienol-rich fraction from palm oil: A systematic review

M Ismail, A Alsalahi, MU Imam, DJ Ooi, H Khaza'Ai… - Nutrients, 2020 - mdpi.com
Background: Several natural products have been reported to elicit beneficial effects against
neurodegenerative disorders due to their vitamin E contents. However, the neuroprotective …