Toxicity induced by ciprofloxacin and enrofloxacin: oxidative stress and metabolism
S Badawy, YQ Yang, Y Liu, MA Marawan… - Critical Reviews in …, 2021 - Taylor & Francis
Abstract Ciprofloxacin (CIP)(human use) and enrofloxacin (ENR)(veterinary use) are
synthetic anti-infectious medications that belong to the second generation of …
synthetic anti-infectious medications that belong to the second generation of …
Pharmacokinetics of oral ciprofloxacin in adult patients: A scoping review
AM Junkert, REL Lazo, F Deffert… - British Journal of …, 2024 - Wiley Online Library
Aims To map the literature on oral ciprofloxacin's pharmacokinetics and its implications for
dose adjustments in specific populations. Methods A scoping review was performed …
dose adjustments in specific populations. Methods A scoping review was performed …
Impact of posaconazole and diltiazem on pharmacokinetics of encorafenib, a BRAF V600 kinase inhibitor for melanoma and colorectal cancer with BRAF mutations
E Hahn, R Chavira, L Wollenberg… - Clinical and …, 2023 - Wiley Online Library
Encorafenib is a potent and selective ATP competitive inhibitor of BRAF V600–mutant
kinase approved for patients with BRAF‐mutant melanoma and colorectal cancer …
kinase approved for patients with BRAF‐mutant melanoma and colorectal cancer …
Antidepressant-induced akathisia-related homicides associated with diminishing mutations in metabolizing genes of the CYP450 family
Y Lucire, C Crotty - Pharmacogenomics and personalized medicine, 2011 - Taylor & Francis
Purpose: To examine the relation between variant alleles in 3 CYP450 genes (CYP2D6,
CYP2C9 and CYP2C19), interacting drugs and akathisia in subjects referred to a forensic …
CYP2C9 and CYP2C19), interacting drugs and akathisia in subjects referred to a forensic …
Improving antibacterial prescribing safety in the management of COPD exacerbations: systematic review of observational and clinical studies on potential drug …
Y Wang, MA Bahar, AME Jansen… - Journal of …, 2019 - academic.oup.com
Background Guidelines advise the use of antibacterials (ABs) in the management of COPD
exacerbations. COPD patients often have multiple comorbidities, such as diabetes mellitus …
exacerbations. COPD patients often have multiple comorbidities, such as diabetes mellitus …
[HTML][HTML] Effects of itraconazole and rifampicin on the pharmacokinetics and safety of youkenafil, a novel phosphodiesterase type 5 inhibitor, in healthy Chinese …
K Wang, J Ding, X Li, W Guo, X Zhu, Y Su, L Sun… - European Journal of …, 2022 - Elsevier
Youkenafil is a novel selective phosphodiesterase type 5 inhibitor to treat erectile
dysfunction. In order to study the drug-drug interactions of youkenafil, in vitro experiments …
dysfunction. In order to study the drug-drug interactions of youkenafil, in vitro experiments …
A quantitative analysis of the spontaneous reporting of congestive heart failure‐related adverse events with systemic anti‐fungal drugs
M Hauben, EY Hung - The Journal of Clinical Pharmacology, 2013 - Wiley Online Library
To investigate spontaneous reporting relationships between representative antifungal
agents and congestive heart failure (CHF)‐related adverse events (AE) we performed …
agents and congestive heart failure (CHF)‐related adverse events (AE) we performed …
Pharmacokinetics of sunitinib in combination with fluoroquinolones in rabbit model
E Szałek, A Karbownik, T Grabowski, K Sobańska… - Pharmacological …, 2013 - Elsevier
Background Fluoroquinolones are widely prescribed antibiotics. Ciprofloxacin is a well-
known inhibitor of cytochrome P450 CYP3A4 and causes numerous drug interactions that …
known inhibitor of cytochrome P450 CYP3A4 and causes numerous drug interactions that …
Quinolones
DRP Guay - Drug interactions in infectious diseases, 2011 - Springer
Fluoroquinolone (FQ) antimicrobials are among the most commonly used agents in the
outpatient and institutional patient care environments. Due to this high frequency of …
outpatient and institutional patient care environments. Due to this high frequency of …
Fluoroquinolone antibiotic prophylaxis to prevent post-traumatic bacterial infectious endophthalmitis: using Monte Carlo simulation to evaluate the probability of …
C Peragine, SAN Walker, S Walker… - Journal of Ocular …, 2019 - liebertpub.com
Purpose: Patients with open globe injuries routinely receive fluoroquinolone (FQ)
prophylaxis to prevent bacterial infectious endophthalmitis. Owing to the rarity of this …
prophylaxis to prevent bacterial infectious endophthalmitis. Owing to the rarity of this …