Insulin resistance is a main determinant in the development of type 2 diabetes mellitus and a
major cause of morbidity and mortality. The circadian timing system consists of a central …

Scientists, public health and school officials are paying growing attention to the mechanism
underlying the delayed sleep patterns common in human adolescents. Data suggest that a …

Circadian rhythms influence most of our life activities, notably getting up and going to sleep
every day. The new edition of this book delves into the mechanisms surrounding how these …

Purpose It has been well established in mammals that circadian behavior as well as the
molecular clockwork can be synchronized to the light-dark (LD) cycle via the …

Shiftwork is associated with adverse metabolic pathophysiology, and the rising incidence of
shiftwork in modern societies is thought to contribute to the worldwide increase in obesity …

Dopamine (DA) neurotransmission controls behaviors important for survival, including
voluntary movement, reward processing, and detection of salient events, such as food or …

Key points Disruptions in circadian rhythms across an organism are associated with
negative health outcomes, such as cardiometabolic and neurodegenerative diseases …

Background Circadian disturbance (CD) is the consequence of a mismatch between
endogenous circadian rhythms, behaviour, and/or environmental cycles, and frequently …

The mammalian circadian clock regulates the day and night cycles of various physiological
functions. The circadian clock system consists of a central clock in the suprachiasmatic …

Exercise during the inactive period can entrain locomotor activity and peripheral circadian
clock rhythm in mice; however, mechanisms underlying this entrainment are yet to be …