At the advent of cross-coupling chemistry, carbon electrophiles based on halides or
pseudohalides were the only suitable electrophilic coupling partners. Almost two decades …

Aza-Heck cyclizations are an emerging method for the construction of chiral N-heterocyclic
systems. In these processes, an activated N–O bond replaces the C–X bond (X= halide, OTf) …

Nitrogen (N) is ubiquitously found in bioactive molecules, pharmaceutical agents, and
organic functional materials. Accordingly, development of new C–N bond-forming catalysis …

A metal-and reagent-free, electrochemical intramolecular oxidative amination reaction of tri-
and tetrasubstituted alkenes has been developed. The electrosynthetic method proceeds …

A nickel-catalyzed 1, 2-aminoarylation of oxime-ester-tethered alkenes with boronic acids
was developed. A variety of pyrroline derivatives were synthesized in good yields via the …

Internal alkynes have been used widely in transition-metal-catalyzed cycloaddition
reactions, in which they generally serve as two-carbon reaction partners. Herein, we report …

An intermolecular anti-Markovnikov hydroamination of alkenes has been developed using
triethyl phosphite and N-hydroxyphthalimide. The process tolerates a wide range of alkenes …

Classical amination methods involve the reaction of a nitrogen nucleophile with an
electrophilic carbon center; however, in recent years, umpoled strategies have gained …

Conventional approaches on using hydroxylamine derivatives as single nitrogen sources,
for the construction of n-membered (n> 3) N-heterocycles, rely upon two chemical …

Carbocation intermediacy is postulated in numerous organic transformations and provides
the foundation for retrosynthetic logics in chemical synthesis. Although a number of catalytic …