Individuals who are diagnosed with amyotrophic lateral sclerosis (ALS) today face the same
historically intransigent problem that has existed since the initial description of the disease in …

Amyotrophic lateral sclerosis (ALS) is a rapidly progressive neurodegenerative disorder
affecting upper and lower motor neurons, with death resulting mainly from respiratory failure …

Whether and how certain transposable elements with viral origins, such as endogenous
retroviruses (ERVs) dormant in our genomes, can become awakened and contribute to the …

Endogenous retroviruses (ERVs) are evolutionary remnants of retroviral infections in which
the viral genome became embedded as a dormant regulatory element within the host …

Amyotrophic lateral sclerosis (ALS) is a rapidly debilitating fatal neurodegenerative disorder,
causing muscle atrophy and weakness, which leads to paralysis and eventual death. ALS …

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder of adult life, causing
weakness and wasting of voluntary muscles, associated in about 50% of cases with a …

Motor neuron diseases (MNDs) are etiologically and biologically heterogeneous diseases.
The pathobiology of motor neuron degeneration is still largely unknown, and no effective …

Objective Human endogenous retroviruses have been implicated in neurodegenerative
diseases including amyotrophic lateral sclerosis (ALS). Expression of human endogenous …

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Neurodegenerative diseases (NDs), including the most prevalent Alzheimer's disease and
Parkinson disease, share common pathological features. Despite decades of gene‐centric …