[HTML][HTML] Polymer translocation: the first two decades and the recent diversification

VV Palyulin, T Ala-Nissila, R Metzler - Soft matter, 2014 - pubs.rsc.org
Probably no other field of statistical physics at the borderline of soft matter and biological
physics has caused such a flurry of papers as polymer translocation since the 1994 …

Direct observation of DNA knots using a solid-state nanopore

C Plesa, D Verschueren, S Pud, J Van Der Torre… - Nature …, 2016 - nature.com
Long DNA molecules can self-entangle into knots. Experimental techniques for observing
such DNA knots (primarily gel electrophoresis) are limited to bulk methods and circular …

Data analysis methods for solid-state nanopores

C Plesa, C Dekker - Nanotechnology, 2015 - iopscience.iop.org
We describe a number of techniques for the analysis of solid-state nanopore ionic current
traces and introduce a new package of Matlab analysis scripts with GUI front ends. We …

Detection of individual proteins bound along DNA using solid-state nanopores

C Plesa, JW Ruitenberg, MJ Witteveen, C Dekker - Nano letters, 2015 - ACS Publications
DNA in cells is heavily covered with all types of proteins that regulate its genetic activity.
Detection of DNA-bound proteins is a challenge that is well suited to solid-state nanopores …

Velocity of DNA during translocation through a solid-state nanopore

C Plesa, N Van Loo, P Ketterer, H Dietz, C Dekker - Nano letters, 2015 - ACS Publications
While understanding translocation of DNA through a solid-state nanopore is vital for
exploiting its potential for sensing and sequencing at the single-molecule level, surprisingly …

Multiplexed DNA identification using site specific dCas9 barcodes and nanopore sensing

NE Weckman, N Ermann, R Gutierrez, K Chen… - ACS …, 2019 - ACS Publications
Decorating double-stranded DNA with dCas9 barcodes to identify characteristic short
sequences provides an alternative to fully sequencing DNA samples for rapid and highly …

[HTML][HTML] Asymmetric dynamics of DNA entering and exiting a strongly confining nanopore

NAW Bell, K Chen, S Ghosal, M Ricci… - Nature …, 2017 - nature.com
In nanopore sensing, changes in ionic current are used to analyse single molecules in
solution. The translocation dynamics of polyelectrolytes is of particular interest given …

DNA Carrier-Assisted Molecular Ping-Pong in an Asymmetric Nanopore

F Zheng, M Alawami, J Zhu, CM Platnich, J Sha… - Nano Letters, 2023 - ACS Publications
Nanopore analysis relies on ensemble averaging of translocation signals obtained from
numerous molecules, requiring a relatively high sample concentration and a long …

On-demand delivery of single DNA molecules using nanopipets

AP Ivanov, P Actis, P Jonsson, D Klenerman… - ACS …, 2015 - ACS Publications
Understanding the behavioral properties of single molecules or larger scale populations
interacting with single molecules is currently a hotly pursued topic in nanotechnology. This …

Selective detection and quantification of modified DNA with solid-state nanopores

AT Carlsen, OK Zahid, JA Ruzicka, EW Taylor… - Nano Letters, 2014 - ACS Publications
We demonstrate a solid-state nanopore assay for the unambiguous discrimination and
quantification of modified DNA. Individual streptavidin proteins are employed as high-affinity …