Oligodendrocyte precursor cells (OPCs) account for 5% of the resident parenchymal central
nervous system glial cells. OPCs are not only a back-up for the loss of oligodendrocytes that …

Remyelination failure contributes to axonal loss and progression of disability in multiple
sclerosis. The failed repair process could be due to ongoing toxic neuroinflammation and to …

Alzheimer's disease (AD) is a neurodegenerative disorder with neuronal and synaptic
losses due to the accumulation of toxic amyloid β (Αβ) peptide oligomers, plaques, and …

Myelin is the lipid-rich structure formed by oligodendrocytes (OLs) that wraps the axons in
multilayered sheaths, assuring protection, efficient saltatory signal conduction and metabolic …

Nervonic acid, a 24-carbon fatty acid with only one double bond at the 9th carbon (C24: 1n-
9), is abundant in the human brain, liver, and kidney. It not only functions in free form but …

Perinatal white matter injury (WMI) is the most common brain injury in premature infants and
can lead to life-long neurological deficits such as cerebral palsy. Preterm birth is typically …

Stem cell therapies for nervous system disorders are hindered by a lack of accessible
autologous sources of neural stem cells (NSCs). In this study, neural crest–derived Schwann …

Multiple sclerosis (MS) is a chronic neurological disease driven by autoimmune,
inflammatory and neurodegenerative processes leading to neuronal demyelination and …

Thyroid hormones (THs) play an important role in the regulation of energy metabolism. They
also take part in processes associated with the central nervous system (CNS), including …

Intracortical microelectrodes have become a useful tool in neuroprosthetic applications in
the clinic and to understand neurological disorders in basic neurosciences. Many of these …