Oxidative stress and impaired oligodendrocyte precursor cell differentiation in neurological disorders
Oligodendrocyte precursor cells (OPCs) account for 5% of the resident parenchymal central
nervous system glial cells. OPCs are not only a back-up for the loss of oligodendrocytes that …
nervous system glial cells. OPCs are not only a back-up for the loss of oligodendrocytes that …
The extracellular matrix as modifier of neuroinflammation and remyelination in multiple sclerosis
S Ghorbani, VW Yong - Brain, 2021 - academic.oup.com
Remyelination failure contributes to axonal loss and progression of disability in multiple
sclerosis. The failed repair process could be due to ongoing toxic neuroinflammation and to …
sclerosis. The failed repair process could be due to ongoing toxic neuroinflammation and to …
Myelin in Alzheimer's disease: culprit or bystander?
M Maitre, H Jeltsch-David, NG Okechukwu… - Acta Neuropathologica …, 2023 - Springer
Alzheimer's disease (AD) is a neurodegenerative disorder with neuronal and synaptic
losses due to the accumulation of toxic amyloid β (Αβ) peptide oligomers, plaques, and …
losses due to the accumulation of toxic amyloid β (Αβ) peptide oligomers, plaques, and …
Oligodendrocyte dysfunction in amyotrophic lateral sclerosis: mechanisms and therapeutic perspectives
S Raffaele, M Boccazzi, M Fumagalli - Cells, 2021 - mdpi.com
Myelin is the lipid-rich structure formed by oligodendrocytes (OLs) that wraps the axons in
multilayered sheaths, assuring protection, efficient saltatory signal conduction and metabolic …
multilayered sheaths, assuring protection, efficient saltatory signal conduction and metabolic …
Nervonic acid and its sphingolipids: Biological functions and potential food applications
NV Phung, F Rong, WY Xia, Y Fan, XY Li… - Critical reviews in …, 2023 - Taylor & Francis
Nervonic acid, a 24-carbon fatty acid with only one double bond at the 9th carbon (C24: 1n-
9), is abundant in the human brain, liver, and kidney. It not only functions in free form but …
9), is abundant in the human brain, liver, and kidney. It not only functions in free form but …
Oligodendrocyte development and implication in perinatal white matter injury
M Motavaf, X Piao - Frontiers in Cellular Neuroscience, 2021 - frontiersin.org
Perinatal white matter injury (WMI) is the most common brain injury in premature infants and
can lead to life-long neurological deficits such as cerebral palsy. Preterm birth is typically …
can lead to life-long neurological deficits such as cerebral palsy. Preterm birth is typically …
Schwann cells in the subcutaneous adipose tissue have neurogenic potential and can be used for regenerative therapies
Stem cell therapies for nervous system disorders are hindered by a lack of accessible
autologous sources of neural stem cells (NSCs). In this study, neural crest–derived Schwann …
autologous sources of neural stem cells (NSCs). In this study, neural crest–derived Schwann …
Disrupted lipid metabolism in multiple sclerosis: a role for liver X receptors?
I Pineda-Torra, S Siddique, KE Waddington… - Frontiers in …, 2021 - frontiersin.org
Multiple sclerosis (MS) is a chronic neurological disease driven by autoimmune,
inflammatory and neurodegenerative processes leading to neuronal demyelination and …
inflammatory and neurodegenerative processes leading to neuronal demyelination and …
Relationship between thyroid hormones and central nervous system metabolism in physiological and pathological conditions
N Sawicka-Gutaj, N Zawalna, P Gut… - Pharmacological Reports, 2022 - Springer
Thyroid hormones (THs) play an important role in the regulation of energy metabolism. They
also take part in processes associated with the central nervous system (CNS), including …
also take part in processes associated with the central nervous system (CNS), including …
Pro-myelinating Clemastine administration improves recording performance of chronically implanted microelectrodes and nearby neuronal health
Intracortical microelectrodes have become a useful tool in neuroprosthetic applications in
the clinic and to understand neurological disorders in basic neurosciences. Many of these …
the clinic and to understand neurological disorders in basic neurosciences. Many of these …