Placebos in chronic pain: evidence, theory, ethics, and use in clinical practice

TJ Kaptchuk, CC Hemond, FG Miller - bmj, 2020 - bmj.com
Despite their ubiquitous presence, placebos and placebo effects retain an ambiguous and
unsettling presence in biomedicine. Specifically focused on chronic pain, this review …

Psychological treatments and psychotherapies in the neurorehabilitation of pain: evidences and recommendations from the Italian Consensus Conference on Pain in …

G Castelnuovo, EM Giusti, GM Manzoni… - Frontiers in …, 2016 - frontiersin.org
Background: It is increasingly recognized that treating pain is crucial for effective care within
neurological rehabilitation in the setting of the neurological rehabilitation. The Italian …

Is the rationale more important than deception? A randomized controlled trial of open-label placebo analgesia

C Locher, AF Nascimento, I Kirsch, J Kossowsky… - Pain, 2017 - journals.lww.com
Research on open-label placebos questions whether deception is a necessary
characteristic of placebo effects. Yet, comparisons between open-label and deceptive …

[HTML][HTML] Dronabinol is a safe long-term treatment option for neuropathic pain patients

S Schimrigk, M Marziniak, C Neubauer, EM Kugler… - European …, 2017 - karger.com
Abstract Treatment of neuropathic pain (NP) symptoms associated with multiple sclerosis
(MS) is frequently insufficient. Yet, cannabis is still rarely offered for treatment of pain. This …

Precision medicine is not just genomics: the right dose for every patient

RW Peck - Annual review of pharmacology and toxicology, 2018 - annualreviews.org
Genomics has helped to initiate the era of precision medicine, with some drugs now
prescribed on the basis of molecular genetic tests that indicate which patients are likely to …

[HTML][HTML] Challenges of differential placebo effects in contemporary medicine: the example of brain stimulation

MJ Burke, TJ Kaptchuk, A Pascual-Leone - Annals of neurology, 2019 - ncbi.nlm.nih.gov
Abstract 'Differential placebo effects' is the concept that different types of placebos (eg inert
pill versus sham device) may yield different magnitudes of placebo effects. This issue has …

Targeting inflammation as a treatment modality for neuropathic pain in spinal cord injury: a randomized clinical trial

DJ Allison, A Thomas, K Beaudry, DS Ditor - Journal of neuroinflammation, 2016 - Springer
Background The purpose of the present study was to examine the effectiveness of an anti-
inflammatory intervention as a treatment for neuropathic pain following spinal cord injury …

EEG correlates of self-managed neurofeedback treatment of central neuropathic pain in chronic spinal cord injury

A Vučković, MKH Altaleb, M Fraser… - Frontiers in …, 2019 - frontiersin.org
Background Neurofeedback (NFB) is a neuromodulatory technique that enables voluntary
modulation of brain activity in order to treat neurological condition, such as central …

What is the role of the placebo effect for pain relief in neurorehabilitation? Clinical implications from the Italian consensus conference on pain in neurorehabilitation

G Castelnuovo, EM Giusti, GM Manzoni… - Frontiers in …, 2018 - frontiersin.org
Background It is increasingly acknowledged that the outcomes of medical treatments are
influenced by the context of the clinical encounter through the mechanisms of the placebo …

Learning pain in context: Response-conditioned placebo analgesia and nocebo hyperalgesia in male rats with chronic neuropathic pain

DC Boorman, KA Keay - Physiology & behavior, 2023 - Elsevier
Background Animal models of placebo analgesia and nocebo hyperalgesia have great
potential to assist in the development of novel treatments for chronic pain that exploit or …