The local extension of cancer cells along nerves is a frequent clinical finding for various
tumours. Traditionally, nerve invasion was assumed to occur via the path of least resistance; …

Recognition molecules of the immunoglobulin superfamily have important roles in neuronal
interactions during ontogeny, including migration, survival, axon guidance and synaptic …

Metastatic neuroblastoma is a poor-prognosis malignancy arising during childhood that
overexpresses the L1-cell adhesion molecule (CD171). We have previously described a …

Cancer is a major health problem around the world. Research efforts in the last few decades
have been successful in providing better and effective treatments against both early stage …

L1 cell adhesion molecule (L1CAM) is one of the first neural adhesion molecules described
with important functions in the development of the nervous system. Subsequent work …

The L1 cell adhesion molecule (L1CAM) plays a major role in the development of the
nervous system and in the malignancy of human tumors. In terms of biological function …

Aberrant β-catenin-TCF target gene activation plays a key role in colorectal cancer, both in
the initiation stage and during invasion and metastasis. We identified the neuronal cell …

Neural cell adhesion molecules (CAMs) of the immunoglobulin superfamily engage in
multiple neuronal interactions that influence cell migration, axonal and dendritic projection …

The immunoglobulin superfamily recognition molecule L1 plays important functional roles in
the developing and adult nervous system. Metalloprotease-mediated cleavage of this …

Background L1 cell adhesion molecule (L1CAM) expression has been implicated as risk
factor for disease recurrence in endometrial cancer (EC), most likely due to its role in …