Astroglia are a broad class of neural parenchymal cells primarily dedicated to homoeostasis
and defence of the central nervous system (CNS). Astroglia contribute to the …

As the professional phagocytes of the brain, microglia orchestrate the immunological
response and play an increasingly important role in maintaining homeostatic brain functions …

Major depressive disorder (MDD) is a common, heterogenous, and potentially serious
psychiatric illness. Diverse brain cell types have been implicated in MDD etiology …

Neurodegenerative diseases and depression are multifactorial disorders with a complex
and poorly understood physiopathology. Astrocytes play a key role in the functioning of …

Postmortem investigations have implicated astrocytes in many neurological and psychiatric
conditions. Multiple brain regions from individuals with major depressive disorder (MDD) …

The neurovascular unit (NVU) is a dynamic center for substance exchange between the
blood and the brain, making it an essential gatekeeper for central nervous system (CNS) …

Over the last 15 years, the field of neuroscience has evolved toward recognizing the critical
role of astroglia in shaping neuronal synaptic activity and along with the pre-and …

Iron plays a fundamental role in multiple brain disorders. However, the genetic
underpinnings of brain iron and its implications for these disorders are still lacking. Here, we …

Astrocytes are the most abundant glial cell type in the central nervous system and are
essential to the development, plasticity, and maintenance of neural circuits. Astrocytes are …

Astrocytes comprise half of the cells in the central nervous system and play a critical role in
maintaining metabolic homeostasis. Metabolic dysfunction in astrocytes has been indicated …