On what motivates us: a detailed review of intrinsic v. extrinsic motivation
Motivational processes underlie behaviors that enrich the human experience, and
impairments in motivation are commonly observed in psychiatric illness. While motivated …
impairments in motivation are commonly observed in psychiatric illness. While motivated …
[HTML][HTML] The brain on drugs: from reward to addiction
ND Volkow, M Morales - Cell, 2015 - cell.com
Advances in neuroscience identified addiction as a chronic brain disease with strong
genetic, neurodevelopmental, and sociocultural components. We here discuss the circuit …
genetic, neurodevelopmental, and sociocultural components. We here discuss the circuit …
Reward, addiction, withdrawal to nicotine
M De Biasi, JA Dani - Annual review of neuroscience, 2011 - annualreviews.org
Nicotine is the principal addictive component that drives continued tobacco use despite
users' knowledge of the harmful consequences. The initiation of addiction involves the …
users' knowledge of the harmful consequences. The initiation of addiction involves the …
Smoking, quitting, and psychiatric disease: a review
HJ Aubin, H Rollema, TH Svensson… - … & Biobehavioral Reviews, 2012 - Elsevier
Tobacco smoking among patients with psychiatric disease is more common than in the
general population, due to complex neurobiological, psychological, and …
general population, due to complex neurobiological, psychological, and …
15 years of genetic approaches in vivo for addiction research: Opioid receptor and peptide gene knockout in mouse models of drug abuse
P Charbogne, BL Kieffer, K Befort - Neuropharmacology, 2014 - Elsevier
The endogenous opioid system is expressed throughout the brain reinforcement circuitry,
and plays a major role in reward processing, mood control and the development of …
and plays a major role in reward processing, mood control and the development of …
[HTML][HTML] Chronic high-fat diet drives postnatal epigenetic regulation of μ-opioid receptor in the brain
Opioid system dysregulation has been observed in both genetic and high-fat diet (HFD)-
induced models of obesity. An understanding of the molecular mechanisms of MOR …
induced models of obesity. An understanding of the molecular mechanisms of MOR …
[HTML][HTML] Methyl donor supplementation blocks the adverse effects of maternal high fat diet on offspring physiology
JL Carlin, R George, TM Reyes - PloS one, 2013 - journals.plos.org
Maternal consumption of a high fat diet during pregnancy increases the offspring risk for
obesity. Using a mouse model, we have previously shown that maternal consumption of a …
obesity. Using a mouse model, we have previously shown that maternal consumption of a …
[HTML][HTML] Smoking behaviour and mental health disorders—mutual influences and implications for therapy
A Minichino, FS Bersani, WK Calò, F Spagnoli… - International Journal of …, 2013 - mdpi.com
Tobacco use is strongly associated with a variety of psychiatric disorders. Smokers are more
likely than non-smokers to meet current criteria for mental health conditions, such as mood …
likely than non-smokers to meet current criteria for mental health conditions, such as mood …
Marked global reduction in mGluR5 receptor binding in smokers and ex-smokers determined by [11C]ABP688 positron emission tomography
F Akkus, SM Ametamey, V Treyer… - Proceedings of the …, 2013 - National Acad Sciences
Nicotine addiction is a major public health problem, resulting in primary glutamatergic
dysfunction. We measured the glutamate receptor binding in the human brain and provided …
dysfunction. We measured the glutamate receptor binding in the human brain and provided …
[HTML][HTML] Prior exposure to THC increases the addictive effects of nicotine in rats
LV Panlilio, C Zanettini, C Barnes, M Solinas… - …, 2013 - nature.com
Although it is more common for drug abuse to progress from tobacco to cannabis, in many
cases cannabis use develops before tobacco use. Epidemiological evidence indicates that …
cases cannabis use develops before tobacco use. Epidemiological evidence indicates that …