Kaposi sarcoma–associated herpesvirus (KSHV), also known as human herpesvirus 8, is
the etiologic agent underlying Kaposi sarcoma, primary effusion lymphoma, and multicentric …

Gammaherpesviruses are an important class of oncogenic pathogens that are exquisitely
evolved to their respective hosts. As such, the human gammaherpesviruses Epstein-Barr …

Mass cytometry has revolutionized the study of cellular and phenotypic diversity, significantly
expanding the number of phenotypic and functional characteristics that can be measured at …

Eukaryotic cells produce several classes of long and small noncoding RNA (ncRNA). Many
DNA and RNA viruses synthesize their own ncRNAs. Like their host counterparts, viral …

Patient-derived xenograft (PDX) tumor models have emerged as a new approach to
evaluate the effects of cancer drugs on patients' personalized tumor grafts enabling to select …

Megalocytivirus is a DNA virus that is highly infectious in a wide variety of marine and
freshwater fish, including Japanese flounder (Paralichthys olivaceus), a flatfish that is farmed …

Dysfunction of ribosome biogenesis induces divergent ribosome‐related diseases including
ribosomopathy and occasionally results in carcinogenesis. Although many defects in …

Patient-derived preclinical models are now a core component of cancer research and have
the ability to drastically improve the predictive power of preclinical therapeutic studies …

Small non-coding RNAs include powerful regulators of gene expression, transposon
mobility and virus activity. Among the various categories, mature microRNAs (miRNAs) …

Gammaherpesviruses, including the human pathogens Epstein-Barr virus (EBV) and
Kaposi's sarcoma-associated herpesvirus (KSHV), establish lifelong latent infection in B …