Cancer is the second leading cause of death in the US. Current major treatments for cancer
management include surgery, cytotoxic chemotherapy, targeted therapy, radiation therapy …

Cancer stem cells (CSCs) are a population of self-renewal cells with high tumorigenic
potency. CSCs can adopt easily with changes in the nearby milieu, and are more resistant to …

Brain tumor is one of the most lethal cancers owing to the existence of blood–brain barrier
and blood–brain tumor barrier as well as the lack of highly effective brain tumor treatment …

After cardiovascular disease, cancer is the leading cause of death worldwide with
devastating health and economic consequences, particularly in developing countries. Inter …

Glioblastoma (GBM) is the highest-grade form of glioma, as well as one of the most
aggressive types of cancer, exhibiting rapid cellular growth and highly invasive behavior …

Glioblastoma (GBM) is one of the most aggressive and lethal human brain tumors. At
present, GBMs are divided in primary and secondary on the basis of the mutational status of …

Cancer stem cells (CSCs), known also as tumor-initiating cells, are quiescent, pluripotent,
self-renewing neoplastic cells that were first identified in hematologic tumors and soon after …

Glioblastoma (GBM) is a highly malignant brain tumor characterized by a heterogeneous
population of genetically unstable and highly infiltrative cells that are resistant to …

Glioblastoma is a highly angiogenetic malignancy, the neoformed vessels of which are
thought to arise by sprouting of pre-existing brain capillaries. The recent demonstration that …

Brain tumor initiating cells (BTICs) co-opt the neuronal high affinity glucose transporter,
GLUT3, to withstand metabolic stress. We investigated another mechanism critical to brain …