Peptides are biopolymers, typically consisting of 2–50 amino acids. They are biologically
produced by the cellular ribosomal machinery or by non-ribosomal enzymes and …

The discovery of enzyme-derived d-amino acid-containing peptides (DAACPs) that have
physiological importance in the metazoan challenges previous assumptions about the …

Information accumulated over the past decades on the physiological functions and
metabolic pathways of biosynthesis and degradation of D-amino acids has led to a renewed …

Proteinaceous aggregation is a well-known observable in Alzheimer's disease (AD), but
failure and storage of lysosomal bodies within neurons is equally ubiquitous and actually …

The protostome leucokinin (LK) signaling system, including LK peptides and their G protein-
coupled receptors, has been characterized in several species. Despite the progress …

The l-to d-amino acid residue isomerization of neuropeptides is an understudied post-
translational modification found in animals across several phyla. Despite its physiological …

Neuropeptides, as pervasive intercellular signaling molecules in the CNS, modulate a
variety of behavioral systems in both protostomes and deuterostomes. Allatostatins are …

l-to d-residue isomerization is a post-translational modification (PTM) present in
neuropeptides, peptide hormones, and peptide toxins from several animals. In most cases …

Neuropeptides are ubiquitous intercellular signaling molecules in the CNS and play diverse
roles in modulating physiological functions by acting on specific G-protein coupled receptors …

d-Amino acid-containing peptides (DAACPs) make up a class of post-translationally
modified peptides in animals that play important roles as cell-to-cell signaling molecules …