Müller cells, the major type of glial cells in the retina, are responsible for the homeostatic and
metabolic support of retinal neurons. By mediating transcellular ion, water, and bicarbonate …

Neural tissue engineering (NTE) is a rapidly progressing field that promises to address
several serious neurological conditions that are currently difficult to treat. Selecting the right …

How cells sense tissue stiffness to guide cell migration is a fundamental question in
development, fibrosis and cancer. Although durotaxis—cell migration towards increasing …

During nervous system development, neurons extend axons along well-defined pathways.
The current understanding of axon pathfinding is based mainly on chemical signaling …

Cholinergic transmission is critical to high-order brain functions such as memory, learning,
and attention. Alzheimer's disease (AD) is characterized by cognitive decline associated …

Physical forces are ubiquitous in biological processes across scales and diverse contexts.
This review highlights the significance of mechanical forces in nervous system development …

Biological cells are well known to respond to a multitude of chemical signals. In the nervous
system, chemical signaling has been shown to be crucially involved in development, normal …

Neural tissue engineering (NTE) has made remarkable strides in recent years and holds
great promise for treating several devastating neurological disorders. Selecting optimal …

Despite their overwhelming complexity, living cells display a high degree of internal
mechanical and functional organization which can largely be attributed to the intracellular …

The development of the nervous system has so far, to a large extent, been considered in the
context of biochemistry, molecular biology and genetics. However, there is growing …