Apoptosis, a type of genetically controlled cell death, is a fundamental cellular mechanism
utilized by multicellular organisms for disposal of cells that are no longer needed or …

Calcium is a versatile and dynamic 2nd messenger that is essential for the survival of all
higher organisms. In cells that undergo activation or excitation, calcium is released from the …

Evolution has exploited the chemical properties of Ca 2+, which facilitate its reversible
binding to the sites of irregular geometry offered by biological macromolecules, to select it as …

Abstract Intracellular calcium (Ca 2+) is an essential second messenger in eukaryotic cells
regulating numerous cellular functions such as contraction, secretion, immunity, growth, and …

MicroRNAs (miRNAs) are small RNAs (∼ 22 bp) that post-transcriptionally regulate protein
expression and are found to be differentially expressed in a number of human cancers …

Mitigating oxidative stress-induced damage is critical to preserve neuronal function in
diseased or injured brains. This study explores the mechanisms contributing to the …

Mitochondrial-associated endoplasmic reticulum (ER) membranes (MAMs) regulate calcium
(Ca2+) homeostasis via Ca2+ transport-related proteins such as inositol-1, 4, 5-triphosphate …

MicroRNAs (miRNAs) are small RNAs (w22bp) that post-transcriptionally regulate protein
expression and are found to be differentially expressed in a number of human cancers …

Amyloid-β (Aβ) is known to exert cytotoxic effects by inducing mitochondrial dysfunction.
Additionally, the mitochondrial voltage-dependent anion channel 1 (VDAC1), which is …

The histological manifestation of growth-regulating and differentiation-inducing signals in
cancer cells is considered as a key component for clinical outcome prediction and …