Endometriosis: Etiology, pathobiology, and therapeutic prospects

PTK Saunders, AW Horne - Cell, 2021 - cell.com
Endometriosis is a common condition associated with infertility that causes chronic pain in
many, but not all, women. It is defined by the presence of endometrial-like tissue outside the …

Pathophysiology, diagnosis, and management of endometriosis

AW Horne, SA Missmer - bmj, 2022 - bmj.com
Endometriosis affects approximately 190 million women and people assigned female at birth
worldwide. It is a chronic, inflammatory, gynecologic disease marked by the presence of …

ESHRE guideline: endometriosis

CM Becker, A Bokor, O Heikinheimo… - Human …, 2022 - academic.oup.com
STUDY QUESTION How should endometriosis be diagnosed and managed based on the
best available evidence from published literature? SUMMARY ANSWER The current …

Endometriosis: epidemiology, classification, pathogenesis, treatment and genetics (review of literature)

B Smolarz, K Szyłło, H Romanowicz - International journal of molecular …, 2021 - mdpi.com
Endometriosis is a “mysterious” disease and its exact cause has not yet been established.
Among the etiological factors, congenital, environmental, epigenetic, autoimmune and …

Endometriosis is a chronic systemic disease: clinical challenges and novel innovations

HS Taylor, AM Kotlyar, VA Flores - The Lancet, 2021 - thelancet.com
Endometriosis is a common disease affecting 5–10% of women of reproductive age globally.
However, despite its prevalence, diagnosis is typically delayed by years, misdiagnosis is …

Rethinking mechanisms, diagnosis and management of endometriosis

C Chapron, L Marcellin, B Borghese… - Nature Reviews …, 2019 - nature.com
Endometriosis is a chronic inflammatory disease defined as the presence of endometrial
tissue outside the uterus, which causes pelvic pain and infertility. This disease should be …

Hormonal treatments for endometriosis: The endocrine background

S Vannuccini, S Clemenza, M Rossi… - Reviews in Endocrine and …, 2022 - Springer
Endometriosis is a benign uterine disorder characterized by menstrual pain and infertility,
deeply affecting women's health. It is a chronic disease and requires a long term …

Once daily oral relugolix combination therapy versus placebo in patients with endometriosis-associated pain: two replicate phase 3, randomised, double-blind, studies …

LC Giudice, S As-Sanie, JCA Ferreira, CM Becker… - The Lancet, 2022 - thelancet.com
Background Endometriosis is a common cause of pelvic pain in women, for which current
treatment options are suboptimal. Relugolix, an oral gonadotropin-releasing hormone …

The burden of endometriosis on women's lifespan: a narrative overview on quality of life and psychosocial wellbeing

L Della Corte, C Di Filippo, O Gabrielli… - International journal of …, 2020 - mdpi.com
Endometriosis is a chronic, inflammatory disease affecting more than 170 million women
worldwide and up to 10% of women of reproductive age. As a consequence of inflammatory …

Progesterone and estrogen signaling in the endometrium: what goes wrong in endometriosis?

RM Marquardt, TH Kim, JH Shin, JW Jeong - International journal of …, 2019 - mdpi.com
In the healthy endometrium, progesterone and estrogen signaling coordinate in a tightly
regulated, dynamic interplay to drive a normal menstrual cycle and promote an embryo …