Astrocytes, neurons, synapses: a tripartite view on cortical circuit development

I Farhy-Tselnicker, NJ Allen - Neural development, 2018 - Springer
In the mammalian cerebral cortex neurons are arranged in specific layers and form
connections both within the cortex and with other brain regions, thus forming a complex …

Structural components of synaptic plasticity and memory consolidation

CH Bailey, ER Kandel… - Cold Spring Harbor …, 2015 - cshperspectives.cshlp.org
Consolidation of implicit memory in the invertebrate Aplysia and explicit memory in the
mammalian hippocampus are associated with remodeling and growth of preexisting …

Prenatal interleukin 6 elevation increases glutamatergic synapse density and disrupts hippocampal connectivity in offspring

F Mirabella, G Desiato, S Mancinelli, G Fossati… - Immunity, 2021 - cell.com
Early prenatal inflammatory conditions are thought to be a risk factor for different
neurodevelopmental disorders. Maternal interleukin-6 (IL-6) elevation during pregnancy …

Increased dendritic spine densities on cortical projection neurons in autism spectrum disorders

JJ Hutsler, H Zhang - Brain research, 2010 - Elsevier
Multiple types of indirect evidence have been used to support theories of altered cortical
connectivity in autism spectrum disorders (ASD). In other developmental disorders reduced …

High-resolution proteomics unravel architecture and molecular diversity of native AMPA receptor complexes

J Schwenk, N Harmel, A Brechet, G Zolles, H Berkefeld… - Neuron, 2012 - cell.com
AMPA-type glutamate receptors (AMPARs) are responsible for a variety of processes in the
mammalian brain including fast excitatory neurotransmission, postsynaptic plasticity, or …

microRNAs at the synapse

G Schratt - Nature Reviews Neuroscience, 2009 - nature.com
MicroRNAs (miRNAs) are emerging as key modulators of post-transcriptional gene
regulation in a plethora of tissues, including the nervous system. Recent evidence points to …

Subcortical brain development in autism and fragile X syndrome: evidence for dynamic, age-and disorder-specific trajectories in infancy

MD Shen, MR Swanson, JJ Wolff… - American Journal of …, 2022 - Am Psychiatric Assoc
Objective: Previous research has demonstrated that the amygdala is enlarged in children
with autism spectrum disorder (ASD). However, the precise onset of this enlargement during …

Mice with Shank3 mutations associated with ASD and schizophrenia display both shared and distinct defects

Y Zhou, T Kaiser, P Monteiro, X Zhang… - Neuron, 2016 - cell.com
Genetic studies have revealed significant overlaps of risk genes among psychiatric
disorders. However, it is not clear how different mutations of the same gene contribute to …

Regional diversity and developmental dynamics of the AMPA-receptor proteome in the mammalian brain

J Schwenk, D Baehrens, A Haupt, W Bildl, S Boudkkazi… - Neuron, 2014 - cell.com
Native AMPA receptors (AMPARs) in the mammalian brain are macromolecular complexes
whose functional characteristics vary across the different brain regions and change during …

[HTML][HTML] Trans-synaptic interaction of GluRδ2 and Neurexin through Cbln1 mediates synapse formation in the cerebellum

T Uemura, SJ Lee, M Yasumura, T Takeuchi, T Yoshida… - Cell, 2010 - cell.com
Elucidation of molecular mechanisms that regulate synapse formation is required for the
understanding of neural wiring, higher brain functions, and mental disorders. Despite the …