Applications of synthetic biology in medical and pharmaceutical fields

X Yan, X Liu, C Zhao, GQ Chen - Signal transduction and targeted …, 2023 - nature.com
Synthetic biology aims to design or assemble existing bioparts or bio-components for useful
bioproperties. During the past decades, progresses have been made to build delicate …

Enzyme‐Polymer Conjugates for Tuning, Enhancing, and Expanding Biocatalytic Activity

M Heredero, A Beloqui - ChemBioChem, 2023 - Wiley Online Library
Combining polymers with functional proteins is an approach that has brought several
successful stories in the field of biomedicine with PEGylated therapeutic proteins. The latest …

Enzyme‐Polymer‐Conjugate‐Based Pickering Emulsions for Cell‐Free Expression and Cascade Biotransformation

H Lu, J Ouyang, WQ Liu, C Wu… - Angewandte Chemie …, 2023 - Wiley Online Library
In this study, we addressed the limitations of conventional enzyme‐polymer‐conjugate‐
based Pickering emulsions for interfacial biocatalysis, which traditionally suffer from …

Biofuels and nanocatalysts: python boosting visualization of similarities

F Gomes Souza Jr, K Pal, JD Ampah, MC Dantas… - Materials, 2023 - mdpi.com
Among the most relevant themes of modernity, using renewable resources to produce
biofuels attracts several countries' attention, constituting a vital part of the global geopolitical …

[HTML][HTML] Lipoic acid-based poly (disulfide) s: Synthesis and biomedical applications

IO Levkovskyi, S Mochizuki, A Zheng, X Zhang… - Nano TransMed, 2023 - Elsevier
Biodegradable and adaptable polymeric materials are currently being studied due to their
wide scope of potential applications, from nanomedicine to novel multifunctional materials …

Co-immobilization of enzymes and chemocatalysts for one-pot chemoenzymatic cascades: Scaffold engineering toward more efficient catalysis

T Chen, Y Lu, X Xiong, Z Xu - Chem Catalysis, 2024 - cell.com
The combination of enzymes and chemocatalysts for one-pot chemoenzymatic cascade
reactions has emerged as a promising field for advancing atom-economic and …

Stapled NRPS enhances the production of valinomycin in Escherichia coli

S Huang, F Ba, WQ Liu, J Li - Biotechnology and …, 2023 - Wiley Online Library
Nonribosomal peptides (NRPs) are a large family of secondary metabolites with notable
bioactivities, which distribute widely in natural resources across microbes and plants. To …

An In Vitro Hybrid Biocatalytic System Enabled by a Combination of Surface-Displayed, Purified, and Cell-Free Expressed Enzymes

Y Liu, S Huang, WQ Liu, F Ba, Y Liu, S Ling… - ACS Synthetic …, 2024 - ACS Publications
Enzymatic cascades have become a green and sustainable approach for the synthesis of
valuable chemicals and pharmaceuticals. Using sequential enzymes to construct a …

Design and Synthesis of Electrocatalysts Base on Catalysis‐Unit Engineering

Z Zhang, Z Zhang, C Chen, R Xu, XB Chen… - Advanced …, 2024 - Wiley Online Library
It is a pressing need to develop new energy materials to address the existing energy crisis.
However, screening optimal targets out of thousands of materials candidates remains a …

Protein–polymer bioconjugation, immobilization, and encapsulation: a comparative review towards applicability, functionality, activity, and stability

B Çalbaş, AN Keobounnam, C Korban… - Biomaterials …, 2024 - pubs.rsc.org
Polymer-based biomaterials have received a lot of attention due to their biomedical,
agricultural, and industrial potential. Soluble protein–polymer bioconjugates, immobilized …