Crosslinking biopolymers for biomedical applications

N Reddy, R Reddy, Q Jiang - Trends in biotechnology, 2015 - cell.com
Biomaterials made from proteins, polysaccharides, and synthetic biopolymers are preferred
but lack the mechanical properties and stability in aqueous environments necessary for …

Functionalizing nanoparticles with biological molecules: developing chemistries that facilitate nanotechnology

KE Sapsford, WR Algar, L Berti, KB Gemmill… - Chemical …, 2013 - ACS Publications
Bionanotechnology has now become firmly established in its own right as one of the
principle and focused subdisciplines within nanotechnology.(1-10) Bionanotechnology can …

Chemical modifications of hyaluronic acid for the synthesis of derivatives for a broad range of biomedical applications

CE Schanté, G Zuber, C Herlin, TF Vandamme - Carbohydrate polymers, 2011 - Elsevier
Hyaluronic acid (HA) is widely used for numerous medical applications, such as
viscosupplementation, eye surgery and drug delivery. A broad range of HA-based materials …

Fate of engineered nanoparticles: implications in the environment

AD Dwivedi, SP Dubey, M Sillanpää, YN Kwon… - Coordination Chemistry …, 2015 - Elsevier
The increased flux of engineered nanoparticles (ENPs) in consumer and commercial
products has become a viable threat, particularly if their release affects the environment. The …

Hyaluronan nanoparticles selectively target plaque-associated macrophages and improve plaque stability in atherosclerosis

TJ Beldman, ML Senders, A Alaarg, C Pérez-Medina… - ACS …, 2017 - ACS Publications
Hyaluronan is a biologically active polymer, which can be formulated into nanoparticles. In
our study, we aimed to probe atherosclerosis-associated inflammation by using hyaluronan …

Insulin-loaded pH-sensitive hyaluronic acid nanoparticles enhance transcellular delivery

L Han, Y Zhao, L Yin, R Li, Y Liang, H Huang, S Pan… - Aaps Pharmscitech, 2012 - Springer
In the present study, we developed novel insulin-loaded hyaluronic acid (HA) nanoparticles
for insulin delivery. The insulin-loaded HA nanoparticles were prepared by reverse …

Fabrication of basil seed gum nanoparticles as a novel oral delivery system of glutathione

S Naji-Tabasi, SMA Razavi, H Mehditabar - Carbohydrate polymers, 2017 - Elsevier
Plant derived polymers like mucilage have evoked great attention in the field of functional
food ingredient delivery. The objective of this study was to evaluate the potential of basil …

A novel crosslinked hyaluronic acid nanogel for drug delivery

SS Pedrosa, C Goncalves, L David… - Macromolecular …, 2014 - Wiley Online Library
An amphiphilic hyaluronic acid conjugate is successfully developed based on grafting a
thiolated hydrophobic molecule to the polysaccharide backbone. The engineered conjugate …

Preparation and characterization of anionic pullulan thermoassociative nanoparticles for drug delivery

G Mocanu, M Nichifor, L Picton, E About-Jaudet… - Carbohydrate …, 2014 - Elsevier
Thermoassociative nanoparticles were obtained through the crosslinking reaction of
periodate oxidized carboxymethyl pullulan with two difunctional Jeffamines: ED-600 and ED …

Advantages of cross-linked versus linear hyaluronic acid for semisolid skin delivery systems

S Berkó, M Maroda, M Bodnár, G Erős… - European polymer …, 2013 - Elsevier
Cross-linking of the hyaluronic acid (hyaluronan, HA) molecule may be a possible chemical
modification via which to improve the problem of the penetration of HA. The successful …