Explainable artificial intelligence for drug discovery and development-a comprehensive survey

R Alizadehsani, SS Oyelere, S Hussain… - IEEE …, 2024 - ieeexplore.ieee.org
The field of drug discovery has experienced a remarkable transformation with the advent of
artificial intelligence (AI) and machine learning (ML) technologies. However, as these AI and …

Mode of action of biogenic silver, zinc, copper, titanium and cobalt nanoparticles against antibiotics resistant pathogens

M Summer, S Ali, HM Tahir, R Abaidullah… - Journal of Inorganic and …, 2024 - Springer
The rapid surge in antibiotic resistance to pathogens has emerged as a grave threat to
public health, globally. This multiple drug resistance (MDR) is directly linked to the high rates …

A separable temporal convolutional networks based deep learning technique for discovering antiviral medicines

V Singh, SK Singh - Scientific Reports, 2023 - nature.com
An alarming number of fatalities caused by the COVID-19 pandemic has forced the scientific
community to accelerate the process of therapeutic drug discovery. In this regard, the …

Continual learning in medical imaging analysis: A comprehensive review of recent advancements and future prospects

P Kumari, J Chauhan, A Bozorgpour, R Azad… - arXiv preprint arXiv …, 2023 - arxiv.org
Medical imaging analysis has witnessed remarkable advancements even surpassing
human-level performance in recent years, driven by the rapid development of advanced …

Artificial intelligence-based model for predicting the minimum inhibitory concentration of antibacterial peptides against ESKAPEE pathogens

R Sharma, S Shrivastava, SK Singh… - IEEE Journal of …, 2023 - ieeexplore.ieee.org
In response to environmental threats, pathogens make several changes in their genome,
leading to antimicrobial resistance (AMR). Due to AMR, the pathogens do not respond to …

Overcoming catastrophic forgetting in molecular property prediction using continual learning of sequential episodes

S Ranjan, SK Singh - Expert Systems with Applications, 2024 - Elsevier
Abstract Continual Learning requires Large Language Models (LLM) to adapt to new
episodes and data over time without forgetting the knowledge acquired from previous …

Multi-label classification to predict antibiotic resistance from raw clinical MALDI-TOF mass spectrometry data

CA Astudillo, XA López-Cortés, E Ocque… - Scientific Reports, 2024 - nature.com
Antimicrobial resistance (AMR) poses a significant global health challenge, necessitating
advanced predictive models to support clinical decision-making. In this study, we explore …

Multiscale Temporal Convolutional Network-Based End-to-End Recognition of Drill-String Stick-Slip Vibration in Drilling Process

X Wu, X Lai, J Hu, C Lu, M Wu - IEEE Transactions on Industrial …, 2024 - ieeexplore.ieee.org
Severe drill-string vibration is a significant source of drilling problems. Most existing methods
for vibration recognition rely on downhole data, facing great limitations in practice. In …

Designing new blood-brain barrier penetrating molecules using novel hybridized gravitational search algorithm and explainable AI

V Singh, R Sharma, SK Singh - IEEE Transactions on Artificial …, 2023 - ieeexplore.ieee.org
Artificial intelligence (AI) has emerged as a powerful tool in computational biology, where it
is being used to analyze large datasets to detect difficult biological patterns. This has …

Antibiotic Bacteria Interaction: Dataset and Benchmarking.

S Chatterjee, A Majumdar, E Chouzenoux - bioRxiv, 2024 - biorxiv.org
This study introduces a dataset for drug-bacteria associations (DBA) that affects humans.
Our contribution extends beyond merely curating the association matrix; we also conduct …