The autonomic nervous system and cardiac arrhythmias: current concepts and emerging therapies

N Herring, M Kalla, DJ Paterson - Nature Reviews Cardiology, 2019 - nature.com
Research into cardiac autonomic control has received great interest in the past 20 years,
and we are now at a critical juncture with regard to the clinical translation of the experimental …

Implications for neuromodulation therapy to control inflammation and related organ dysfunction in COVID-19

M Fudim, YJ Qadri, K Ghadimi, DB MacLeod… - Journal of …, 2020 - Springer
COVID-19 is a syndrome that includes more than just isolated respiratory disease, as severe
acute respiratory syndrome–coronavirus 2 (SARS-CoV2) also interacts with the …

TREAT AF (transcutaneous electrical Vagus nerve stimulation to suppress atrial fibrillation) a randomized clinical trial

S Stavrakis, JA Stoner, MB Humphrey, L Morris… - Clinical …, 2020 - jacc.org
Objectives This study was a sham-controlled, double-blind, randomized clinical trial to
examine the effect of chronic low level tragus stimulation (LLTS) in patients with paroxysmal …

Neuromodulation of inflammation to treat heart failure with preserved ejection fraction: a pilot randomized clinical trial

S Stavrakis, K Elkholey, L Morris… - Journal of the …, 2022 - Am Heart Assoc
Background A systemic proinflammatory state plays a central role in the development of
heart failure with preserved ejection fraction. Low‐level transcutaneous vagus nerve …

Non-invasive vagus nerve stimulation for COVID-19: results from a randomized controlled trial (SAVIOR I)

C Tornero, E Pastor, MM Garzando, J Orduña… - Frontiers in …, 2022 - frontiersin.org
Background Severe coronavirus disease 2019 (COVID-19) is characterized, in part, by an
excessive inflammatory response. Evidence from animal and human studies suggests that …

Pt nanoshells with a high NIR-II photothermal conversion efficiency mediates multimodal neuromodulation against ventricular arrhythmias

C Wang, L Zhou, C Liu, J Qiao, X Han, L Wang… - Nature …, 2024 - nature.com
Autonomic nervous system disorders play a pivotal role in the pathophysiology of
cardiovascular diseases. Regulating it is essential for preventing and treating acute …

The role of the autonomic nervous system in cardiac arrhythmias: the neuro-cardiac axis, more foe than friend?

AA Manolis, TA Manolis, EJ Apostolopoulos… - Trends in cardiovascular …, 2021 - Elsevier
The autonomic nervous system (ANS) with its two limbs, the sympathetic (SNS) and
parasympathetic nervous system (PSNS), plays a critical role in the modulation of cardiac …

Neuroscientific therapies for atrial fibrillation

P Hanna, E Buch, S Stavrakis, C Meyer… - Cardiovascular …, 2021 - academic.oup.com
The cardiac autonomic nervous system (ANS) plays an integral role in normal cardiac
physiology as well as in disease states that cause cardiac arrhythmias. The cardiac ANS …

Research opportunities in autonomic neural mechanisms of cardiopulmonary regulation: a report from the national heart, lung, and blood institute and the national …

R Mehra, OA Tjurmina, OA Ajijola, R Arora… - Basic to Translational …, 2022 - jacc.org
This virtual workshop was convened by the National Heart, Lung, and Blood Institute, in
partnership with the Office of Strategic Coordination of the Office of the National Institutes of …

Vagus nerve stimulation for cardiovascular diseases: Is there light at the end of the tunnel?

S Zafeiropoulos, U Ahmed, A Bikou, IT Mughrabi… - Trends in cardiovascular …, 2024 - Elsevier
Autonomic dysfunction and chronic inflammation contribute to the pathogenesis and
progression of several cardiovascular diseases (CVD), such as heart failure with preserved …