Initially identified as a T lymphocyte-elicited inhibitor of macrophage motility, macrophage
migration inhibitory factor (MIF) has since been found to be expressed by nearly every …

Objectives Bone defects caused by diseases and trauma are usually accompanied by
inflammation, and the implantation of biomaterials as a common repair method has also …

The repair of critical bone defects is a hotspot of orthopedic research. With the development
of bone tissue engineering (BTE), there is increasing evidence showing that the combined …

Nasopharyngeal carcinoma (NPC) is the most common malignant tumor of the head and
neck cancer (HNC). Metastasis is the main cause of treatment failure. However, the …

The malignant microenvironment plays a major role in the development of resistance to
therapies and the occurrence of relapses in acute myeloid leukemia (AML). We previously …

Cancers reprogram macrophages (MΦs) to a tumor-growth-promoting TAM (tumor-
associated MΦ) phenotype that is similar to the anti-inflammatory M2 phenotype. Poly (ADP …

Simple Summary Nasopharyngeal carcinoma (NPC) is a malignancy prevalent in Southeast
Asia with the highest metastatic rate amongst other head and neck cancers. The absence of …

Background Epstein-Barr virus (EBV) is considered a carcinogenic virus, which is
associated with high risk for poor prognosis in lymphoma patients, and there has been …

Head and neck squamous cell carcinoma presents itself as a public health crisis, being the
tenth most diagnosed form of cancer in the United States. Alcohol and tobacco use are …

Tumor-associated macrophages polarized to an M2 phenotype (M2-TAMs) promote neo-
angiogenesis, tumor-stromal matrix remodeling, and immuno-evasion, which, collectively …