miRNAs insights into rheumatoid arthritis: Favorable and detrimental aspects of key performers

AS Doghish, A Ismail, HA El-Mahdy, SY Elkhawaga… - Life Sciences, 2023 - Elsevier
Rheumatoid arthritis (RA) is a severe autoimmune inflammation that mostly affects the joints.
It's a multifactorial disease. Its clinical picture depends on genetic and epigenetic factors …

Rheumatoid arthritis and miRNAs: a critical review through a functional view

MC Moran-Moguel, S Petarra-del Rio… - Journal of …, 2018 - Wiley Online Library
Rheumatoid arthritis (RA) is a systemic autoimmune disease with severe joint inflammation
and destruction associated with an inflammatory environment. The etiology behind RA …

Epigenetic control of autoimmune diseases: from bench to bedside

A Picascia, V Grimaldi, O Pignalosa, MR De Pascale… - Clinical …, 2015 - Elsevier
Genome-wide association studies have revealed several genes predisposing to
autoimmunity, however, concordance rates in monozygotic twins are significantly below …

Possible use of miRNAs-146a and-499 expression and their polymorphisms as diagnostic markers for rheumatoid arthritis

G Ayeldeen, Y Nassar, H Ahmed, O Shaker… - Molecular and cellular …, 2018 - Springer
Rheumatoid arthritis (RA) is a systemic autoimmune disorder affecting the peripheral joints.
Different microRNAs had been investigated in RA including miRNA-146a meanwhile …

[HTML][HTML] The link between type 2 diabetes mellitus and the polymorphisms of glutathione-metabolizing genes suggests a new hypothesis explaining disease initiation …

I Azarova, E Klyosova, A Polonikov - Life, 2021 - mdpi.com
The present study investigated whether type 2 diabetes (T2D) is associated with
polymorphisms of genes encoding glutathione-metabolizing enzymes such as glutathione …

Polymorphisms in STAT-4, IL-10, PSORS1C1, PTPN2 and MIR146A genes are associated differently with prognostic factors in Italian patients affected by rheumatoid …

C Ciccacci, P Conigliaro, C Perricone… - Clinical & …, 2016 - academic.oup.com
Rheumatoid arthritis (RA) is a systemic autoimmune disease resulting in chronic
inflammation of the synovium and consequent cartilage and bone erosion. RA is associated …

[HTML][HTML] Association of polymorphisms rs1800012 in COL1A1 with sports-related tendon and ligament injuries: a meta-analysis

C Wang, H Li, K Chen, B Wu, H Liu - Oncotarget, 2017 - ncbi.nlm.nih.gov
It has been reported that the single nucleotide polymorphism (SNP) rs1800012 in COL1A1
might be associated with the susceptibility to sports-related tendon and ligament injuries …

MicroRNA and human bone health

VKF Cheng, PCM Au, KCB Tan… - Journal of Bone and …, 2019 - academic.oup.com
The small non coding microRNAs (miRNAs) are post transcription regulators that modulate
diverse cellular process in bone cells. Because optimal miRNA targeting is essential for their …

Precursor miR-499a variant but not miR-196a2 is associated with rheumatoid arthritis susceptibility in an Egyptian population

EA Toraih, NM Ismail, AA Toraih, MH Hussein… - Molecular diagnosis & …, 2016 - Springer
Introduction Rheumatoid arthritis (RA) has a complex component induced by several genes
that interact together with environmental and hormonal factors. We aimed to investigate the …

Association of microRNAs genes polymorphisms with arthritis: a systematic review and meta-analysis

Y Xiao, H Liu, L Chen, Y Wang, X Yao… - Bioscience …, 2019 - portlandpress.com
Objective: To investigate whether microRNAs genes' polymorphisms are associated with
arthritis. Methods: The PubMed, Cochrane Library et al. were systematically searched to …