Akkermansia muciniphila: paradigm for next-generation beneficial microorganisms
Ever since Akkermansia muciniphila was discovered and characterized two decades ago,
numerous studies have shown that the lack or decreased abundance of this commensal …
numerous studies have shown that the lack or decreased abundance of this commensal …
[HTML][HTML] Inflammation and aging: signaling pathways and intervention therapies
Aging is characterized by systemic chronic inflammation, which is accompanied by cellular
senescence, immunosenescence, organ dysfunction, and age-related diseases. Given the …
senescence, immunosenescence, organ dysfunction, and age-related diseases. Given the …
Environmental factors shaping the gut microbiome in a Dutch population
The gut microbiome is associated with diverse diseases,–, but a universal signature of a
healthy or unhealthy microbiome has not been identified, and there is a need to understand …
healthy or unhealthy microbiome has not been identified, and there is a need to understand …
[HTML][HTML] Programmable probiotics modulate inflammation and gut microbiota for inflammatory bowel disease treatment after effective oral delivery
J Zhou, M Li, Q Chen, X Li, L Chen, Z Dong… - Nature …, 2022 - nature.com
Reactive oxygen species (ROS) play vital roles in intestinal inflammation. Therefore,
eliminating ROS in the inflammatory site by antioxidant enzymes such as catalase and …
eliminating ROS in the inflammatory site by antioxidant enzymes such as catalase and …
Heart disease and stroke statistics—2022 update: a report from the American Heart Association
Background: The American Heart Association, in conjunction with the National Institutes of
Health, annually reports the most up-to-date statistics related to heart disease, stroke, and …
Health, annually reports the most up-to-date statistics related to heart disease, stroke, and …
[HTML][HTML] Metformin: update on mechanisms of action and repurposing potential
Currently, metformin is the first-line medication to treat type 2 diabetes mellitus (T2DM) in
most guidelines and is used daily by> 200 million patients. Surprisingly, the mechanisms …
most guidelines and is used daily by> 200 million patients. Surprisingly, the mechanisms …
[HTML][HTML] Dietary fibre modulates the gut microbiota
Dietary fibre has long been established as a nutritionally important, health-promoting food
ingredient. Modern dietary practices have seen a significant reduction in fibre consumption …
ingredient. Modern dietary practices have seen a significant reduction in fibre consumption …
Bioaccumulation of therapeutic drugs by human gut bacteria
Bacteria in the gut can modulate the availability and efficacy of therapeutic drugs. However,
the systematic mapping of the interactions between drugs and bacteria has only started …
the systematic mapping of the interactions between drugs and bacteria has only started …
Gut microbiota in human metabolic health and disease
Y Fan, O Pedersen - Nature Reviews Microbiology, 2021 - nature.com
Observational findings achieved during the past two decades suggest that the intestinal
microbiota may contribute to the metabolic health of the human host and, when aberrant, to …
microbiota may contribute to the metabolic health of the human host and, when aberrant, to …
[HTML][HTML] Health and disease markers correlate with gut microbiome composition across thousands of people
Variation in the human gut microbiome can reflect host lifestyle and behaviors and influence
disease biomarker levels in the blood. Understanding the relationships between gut …
disease biomarker levels in the blood. Understanding the relationships between gut …