The role played by ferroptosis in osteoarthritis: evidence based on iron dyshomeostasis and lipid peroxidation

S Zhang, J Xu, H Si, Y Wu, S Zhou, B Shen - Antioxidants, 2022 - mdpi.com
Ferroptosis, a recently discovered regulated cell death modality, is characterised by iron-
dependent accumulation of lipid hydroperoxides, which can reach lethal levels but can be …

Ferroptosis in osteoarthritis: current understanding

Y Liu, Z Zhang, Y Fang, C Liu… - Journal of Inflammation …, 2024 - Taylor & Francis
Osteoarthritis (OA) is a prevalent degenerative disease in elderly people that is
characterized by cartilage loss and abrasion, leading to joint pain and dysfunction. The …

Pterostilbene improves CFA-induced arthritis and peripheral neuropathy through modulation of oxidative stress, inflammatory cytokines and neurotransmitters in …

A Amin, MF Akhtar, A Saleem, A Sharif, S Shah… - …, 2022 - Springer
Pterostilbene is a stilbene flavonoid that occurs naturally in various plants as well as
produced by genetic engineering. It exhibits anti-inflammatory, analgesic, anti-oxidant and …

Niacinamide and undenatured type II collagen modulates the inflammatory response in rats with monoiodoacetate-induced osteoarthritis

K Sahin, O Kucuk, C Orhan, M Tuzcu, AS Durmus… - Scientific reports, 2021 - nature.com
The current work aimed to examine the properties of oral supplementation of niacinamide
and undenatured type II collagen (UCII) on the inflammation and joint pain behavior of rats …

Assessment of the Efficacy of Bone Marrow‐Derived Mesenchymal Stem Cells against a Monoiodoacetate‐Induced Osteoarthritis Model in Wistar Rats

HM Hamdalla, RR Ahmed, SR Galaly… - Stem Cells …, 2022 - Wiley Online Library
Osteoarthritis (OA) of the knee is a debilitating condition that can severely limit an
individual's mobility and quality of life. This study was designed to evaluate the efficacy of …

Forsythoside B alleviates osteoarthritis through the HMGB1/TLR4/NF‐κB and Keap1/Nrf2/HO‐1 pathways

S Li, Y Li, L Hou, L Tang, F Gao - Journal of Biochemical and …, 2024 - Wiley Online Library
Osteoarthritis (OA) is a joint pain and dysfunction syndrome resulting from severe joint
degeneration. Inflammation and degeneration of the articular cartilage are two main features …

Biosynthesis of gold nanoparticles for the treatment of osteoarthritis alone or in combination with Diacerein® in a rat model

MA Abdel-Aziz, HMS Ahmed, AA El-Nekeety… - …, 2021 - Springer
Gold (Au) compounds were used as an effective therapeutic agent for various inflammatory
diseases; however, the use of Au compounds becomes limited because of its association …

The Potential Benefic Effect of Nicotinamide Riboside in Treating a Murine Model of Monoiodoacetate-Induced Knee Osteoarthritis

FL Gherghina, I Mîndrilă, SA Buteică, G Bică… - Journal of Clinical …, 2023 - mdpi.com
Knee osteoarthritis (KOA), one of the most common orthopedic disorders concerning the
adult population worldwide, is a condition characterized by progressive destruction of the …

Identification and validation of immune-related genes in osteoarthritic synovial fibroblasts

Y Dai, L Chen, Z Zhang, X Liu - Heliyon, 2024 - cell.com
Objective OA was generally considered as a non-inflammatory disease dominated by
articular cartilage degeneration. However, the role of synovitis in OA pathogenesis has …

Comparing Effectiveness of Hyaluronic Acid-Chitosan Nanoparticles Encapsulation Versus Hyaluronic Acid Monotherapy in Osteoarthritis Rat Model: Microarray …

SS Kamar, AM ShamsEldeen, SA Hosny… - Microscopy and …, 2023 - academic.oup.com
Osteoarthritis is a debilitating, progressive joint disease linked to lower quality of life and
higher health care costs. This study compared hyaluronic acid-chitosan nanoparticle …