A Century of Prolactin: emerging perspectives as a Metabolic Regulator

T Wu, Y Duan, J Jiang, T Gu… - … Research and Reviews, 2024 - Wiley Online Library
Prolactin, a hormone that has been studied for almost a century, has evolved from a
reproductive regulator to a key player in metabolic health. Initially identified for its lactogenic …

The Metabolic Impact of Nonalcoholic Fatty Liver Disease on Cognitive Dysfunction: A Comprehensive Clinical and Pathophysiological Review

M Giuffrè, N Merli, M Pugliatti, R Moretti - International Journal of …, 2024 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) exponentially affects the global healthcare burden,
and it is currently gaining increasing interest in relation to its potential impact on central …

Alzheimer's disease, a metabolic disorder: Clinical advances and basic model studies

S Zhou, L Tu, W Chen, G Yan… - Experimental and …, 2023 - spandidos-publications.com
Alzheimer's disease (AD) is a type of neurodegenerative disease characterized by cognitive
impairment that is aggravated with age. The pathological manifestations include …

Treatment with a new barbituric acid derivative suppresses diet-induced metabolic dysfunction and non-alcoholic fatty liver disease in mice

FM Suk, FY Hsu, MH Hsu, WC Chiu, CC Fang, TL Chen… - Life Sciences, 2024 - Elsevier
Introduction Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver
disease, often accompanied by obesity, diabetes, and increased risks of depression and …

Impact of insulin resistance on mild cognitive impairment in type 2 diabetes mellitus patients with non-alcoholic fatty liver disease

H Zhang, H Fareeduddin Mohammed Farooqui… - Diabetology & Metabolic …, 2023 - Springer
Aims Insulin resistance (IR) is a pivotal factor in the pathogenesis of type 2 diabetes mellitus
(T2DM) and non-alcoholic fatty liver disease (NAFLD). Nevertheless, the impact of IR on …

Liver-based inter-organ communication: A disease perspective

XY Luo, SQ Ying, Y Cao, Y Jin, F Jin, CX Zheng… - Life Sciences, 2024 - Elsevier
Inter-organ communication through hormones, cytokines and extracellular vesicles (EVs)
has emerged to contribute to the physiological states and pathological processes of the …

Interleukin-5: an indicator of mild cognitive impairment in patients with type 2 diabetes mellitus-a comprehensive investigation ranging from bioinformatics analysis to …

H Zhang, W Zhu, S Yang, T Niu… - Journal of …, 2024 - Springer
Purpose Neuroinflammation constitutes an underlying mechanism for cognitive impairment.
Here, we endeavor to scrutinize the potential contribution of interleukin-5 (IL-5) towards mild …

Mediation analyses link cardiometabolic factors and liver fat with white matter hyperintensities and cognitive performance: A UK Biobank study

DE Askeland-Gjerde, LT Westlye, PJ Andersson… - medRxiv, 2024 - medrxiv.org
Background: Liver fat is associated with cardiometabolic disease, cerebrovascular disease,
and dementia. Cerebrovascular disease, most frequently cerebral small vessel disease …

The Impact of NAFLD-Related Indices on Brain Structure: Insights from Mendelian Randomization and Colocalization Analysis

C Chen, Y Fu, S Gu, J Liu, Y Zheng, Y Li - Available at SSRN 4773249 - papers.ssrn.com
Non-alcoholic fatty liver disease (NAFLD) has complex relationships with brain structure and
neuropsychiatric health. Our study seeks to unravel this complexity using two-sample …