The Molecular Architecture of Pseudomonas aeruginosa Quorum-Sensing Inhibitors
Q Li, S Mao, H Wang, X Ye - Marine Drugs, 2022 - mdpi.com
The survival selection pressure caused by antibiotic-mediated bactericidal and bacteriostatic
activity is one of the important inducements for bacteria to develop drug resistance. Bacteria …
activity is one of the important inducements for bacteria to develop drug resistance. Bacteria …
Quorum Sensing Inhibitors to Quench P. aeruginosa Pathogenicity
M Duplantier, E Lohou, P Sonnet - Pharmaceuticals, 2021 - mdpi.com
The emergence and the dissemination of multidrug-resistant bacteria constitute a major
public health issue. Among incriminated Gram-negative bacteria, Pseudomonas aeruginosa …
public health issue. Among incriminated Gram-negative bacteria, Pseudomonas aeruginosa …
Targeted and Enhanced Antimicrobial Inhibition of Mesoporous ZnO–Ag2O/Ag, ZnO–CuO, and ZnO–SnO2 Composite Nanoparticles
In this work, mesoporous (pore size below 4 nm) composite nanoparticles of ZnO–Ag2O/Ag,
ZnO–CuO, and ZnO–SnO2 of size d≤ 10 nm (dia.) have been synthesized through the in …
ZnO–CuO, and ZnO–SnO2 of size d≤ 10 nm (dia.) have been synthesized through the in …
Evaluation of 4-aminoquinoline derivatives with an n-octylamino spacer as potential multi-targeting ligands for the treatment of Alzheimer's disease
A Matošević, DM Opsenica, M Spasić… - Chemico-biological …, 2023 - Elsevier
The most successful therapeutic strategy in the treatment of Alzheimer's disease (AD) is
directed toward increasing levels of the neurotransmitter acetylcholine (ACh) by inhibition of …
directed toward increasing levels of the neurotransmitter acetylcholine (ACh) by inhibition of …
[HTML][HTML] Novel quinazolinone inhibitors of the Pseudomonas aeruginosa quorum sensing transcriptional regulator PqsR
S Grossman, F Soukarieh, W Richardson, R Liu… - European Journal of …, 2020 - Elsevier
Rising numbers of cases of multidrug-and extensively drug-resistant Pseudomonas
aeruginosa over recent years have created an urgent need for novel therapeutic …
aeruginosa over recent years have created an urgent need for novel therapeutic …
Synthetic non-toxic anti-biofilm agents as a strategy in combating bacterial resistance
RM Hassan, MS Abd El-Maksoud, IAY Ghannam… - European Journal of …, 2023 - Elsevier
The tremendous increase in the bacterial resistance to the available antibiotics is a serious
problem for the treatment of various infections. Biofilm formation in bacteria significantly …
problem for the treatment of various infections. Biofilm formation in bacteria significantly …
Chemical probe of AHL modulators on quorum sensing in Gram-Negative Bacteria and as antiproliferative agents: A review
M Ampomah-Wireko, C Luo, Y Cao, H Wang… - European Journal of …, 2021 - Elsevier
Pathogenic bacteria use an intercellular chemical communication system called quorum
sensing (QS) to control the expression of cellular functions such as virulence factors, biofilm …
sensing (QS) to control the expression of cellular functions such as virulence factors, biofilm …
Copper (II) and zinc (II) complexes with the clinically used fluconazole: comparison of antifungal activity and therapeutic potential
Copper (II) and zinc (II) complexes with clinically used antifungal drug fluconazole
(fcz),{[CuCl2 (fcz) 2]. 5H2O} n, 1, and {[ZnCl2 (fcz) 2]· 2C2H5OH} n, 2, were prepared and …
(fcz),{[CuCl2 (fcz) 2]. 5H2O} n, 1, and {[ZnCl2 (fcz) 2]· 2C2H5OH} n, 2, were prepared and …
Novel quinazolinone disulfide analogues as pqs quorum sensing inhibitors against Pseudomonas aeruginosa
It is well established that the quorum sensing (QS) in Pseudomonas aeruginosa is primarily
responsible for the synthesis and the release of several virulence factors including …
responsible for the synthesis and the release of several virulence factors including …
Novel quinoline‐based derivatives as the PqsR inhibitor against Pseudomonas aeruginosa PAO1
XH Huang, MT She, YH Zhang, YF Liu… - Journal of applied …, 2022 - academic.oup.com
Aims The emerging of drug resistant Pseudomonas aeruginosa is a critical challenge and
renders an urgent action to discover innovative antimicrobial interventions. One of these …
renders an urgent action to discover innovative antimicrobial interventions. One of these …