The canonical antiviral protein oligoadenylate synthetase 1 elicits antibacterial functions by enhancing IRF1 translation
An important property of the host innate immune response during microbial infection is its
ability to control the expression of antimicrobial effector proteins, but how this occurs post …
ability to control the expression of antimicrobial effector proteins, but how this occurs post …
Specialized ribosomes in health and disease
SC Miller, CC MacDonald, MK Kellogg… - International Journal of …, 2023 - mdpi.com
Ribosomal heterogeneity exists within cells and between different cell types, at specific
developmental stages, and occurs in response to environmental stimuli. Mounting evidence …
developmental stages, and occurs in response to environmental stimuli. Mounting evidence …
Annelid adult cell type diversity and their pluripotent cellular origins
P Álvarez-Campos, H García-Castro, E Emili… - Nature …, 2024 - nature.com
Many annelids can regenerate missing body parts or reproduce asexually, generating all
cell types in adult stages. However, the putative adult stem cell populations involved in these …
cell types in adult stages. However, the putative adult stem cell populations involved in these …
K6-linked ubiquitylation marks formaldehyde-induced RNA-protein crosslinks for resolution
AS Rahmanto, CJ Blum, C Scalera, JB Heidelberger… - Molecular Cell, 2023 - cell.com
Reactive aldehydes are produced by normal cellular metabolism or after alcohol
consumption, and they accumulate in human tissues if aldehyde clearance mechanisms are …
consumption, and they accumulate in human tissues if aldehyde clearance mechanisms are …
[HTML][HTML] The lipid transporter HDLBP promotes hepatocellular carcinoma metastasis through BRAF-dependent epithelial-mesenchymal transition
J Yuan, T Lv, J Yang, Z Wu, L Yan, J Yang, Y Shi… - Cancer letters, 2022 - Elsevier
Tumor metastasis is a major cause of cancer mortality. However, little is known regarding the
regulation of abnormal cholesterol metabolism in hepatocellular carcinoma (HCC) …
regulation of abnormal cholesterol metabolism in hepatocellular carcinoma (HCC) …
[HTML][HTML] Nucleic acid-binding KH domain proteins influence a spectrum of biological pathways including as part of membrane-localized complexes
K-Homology domain (KH domain) proteins bind single-stranded nucleic acids, influence
protein–protein interactions of proteins that harbor them, and are found in all kingdoms of …
protein–protein interactions of proteins that harbor them, and are found in all kingdoms of …
Subcellular mRNA kinetic modeling reveals nuclear retention as rate-limiting
Eukaryotic mRNAs are transcribed, processed, translated, and degraded in different
subcellular compartments. Here, we measured mRNA flow rates between subcellular …
subcellular compartments. Here, we measured mRNA flow rates between subcellular …
Translation of circular RNAs
G Margvelani, KAA Maquera, JR Welden… - Nucleic Acids …, 2025 - academic.oup.com
Circular RNAs (circRNAs) are covalently closed RNAs that are present in all eukaryotes
tested. Recent RNA sequencing (RNA-seq) analyses indicate that although generally less …
tested. Recent RNA sequencing (RNA-seq) analyses indicate that although generally less …
RAVER1 hinders lethal EMT and modulates miR/RISC activity by the control of alternative splicing
The RAVER1 protein serves as a co-factor in guiding the polypyrimidine tract-binding
protein (PTBP)-dependent control of alternative splicing (AS). Whether RAVER1 solely acts …
protein (PTBP)-dependent control of alternative splicing (AS). Whether RAVER1 solely acts …
The high-density lipoprotein binding protein HDLBP is an unusual RNA-binding protein with multiple roles in cancer and disease
J Feicht, RP Jansen - RNA biology, 2024 - Taylor & Francis
The high-density lipoprotein binding protein (HDLBP) is the human member of an
evolutionarily conserved family of RNA-binding proteins, the vigilin protein family. These …
evolutionarily conserved family of RNA-binding proteins, the vigilin protein family. These …