Multi-centre discriminating concentration determination of broflanilide and potential for cross-resistance to other public health insecticides in Anopheles vector …

NM Portwood, MF Shayo, PK Tungu, NJ Mbewe… - Scientific Reports, 2022 - nature.com
Novel insecticides are urgently needed to control insecticide-resistant populations of
Anopheles malaria vectors. Broflanilide acts as a non-competitive antagonist of the gamma …

The isotopic composition of the French Illimani ice core in the Bolivian Andes supports the east-west South American precipitation dipole from the last deglaciation to …

F Vimeux, A Landais - Quaternary Science Reviews, 2025 - Elsevier
The age of the deepest part of the French Illimani ice core drilled in 1999 in Bolivia (16.63°
S, 67.78° W) has been attributed to the Last Glacial Maximum (LGM). Major uncertainties …

Identification of two insecticide resistance markers in Ethiopian Anopheles stephensi mosquitoes using a multiplex amplicon sequencing assay

H Acford-Palmer, JE Phelan, FG Tadesse, M Kristan… - Scientific Reports, 2023 - nature.com
Since its first detection in 2012 in Djibouti, Anopheles stephensi has invaded and
established in the Horn of Africa, and more recently Nigeria. The expansion of this vector …

Considerations for first field trials of low-threshold gene drive for malaria vector control

JB Connolly, A Burt, G Christophides, A Diabate… - Malaria Journal, 2024 - Springer
Sustainable reductions in African malaria transmission require innovative tools for mosquito
control. One proposal involves the use of low-threshold gene drive in Anopheles vector …

Phenotypic evidence of deltamethrin resistance and identification of selective sweeps in Anopheles mosquitoes on the Bijagós Archipelago, Guinea-Bissau

S Moss, RT Jones, E Pretorius, ET da Silva… - Scientific reports, 2024 - nature.com
Vector control in the Bijagós Archipelago of Guinea-Bissau currently relies on pyrethroid
insecticide-treated nets. However, data on insecticide resistance in Guinea-Bissau is limited …

Detection of insecticide resistance markers in Anopheles funestus from the Democratic Republic of the Congo using a targeted amplicon sequencing panel

H Acford-Palmer, M Campos, J Bandibabone… - Scientific Reports, 2023 - nature.com
Vector control strategies have been successful in reducing the number of malaria cases and
deaths globally, but the spread of insecticide resistance represents a significant threat to …

High throughput human genotyping for variants associated with malarial disease outcomes using custom targeted amplicon sequencing

A Osborne, JE Phelan, LN Vanheer, A Manjurano… - Scientific Reports, 2023 - nature.com
Malaria has exhibited the strongest known selective pressure on the human genome in
recent history and is the evolutionary driving force behind genetic conditions, such as sickle …

Whole genome sequence analysis of population structure and insecticide resistance markers in Anopheles melas from the Bijagós Archipelago, Guinea-Bissau

S Moss, E Pretorius, S Ceesay, ET da Silva… - Parasites & vectors, 2024 - Springer
Background Anopheles melas is an understudied malaria vector with a potential role in
malaria transmission on the Bijagós Archipelago of Guinea-Bissau. This study presents the …

Pathogen prospecting of museums: Reconstructing malaria epidemiology

MP Nelder, R Schats, HN Poinar… - Proceedings of the …, 2024 - National Acad Sciences
Malaria is a disease of global significance. Ongoing changes to the earth's climate,
antimalarial resistance, insecticide resistance, and socioeconomic decline test the resilience …

Efficacy of chlorfenapyr-pyrethroid and piperonyl butoxide-pyrethroid long-lasting insecticidal nets (LLINs) compared to pyrethroid-only LLINs for malaria control in …

C Sih, N Protopopoff, AA Koffi, LP Ahoua Alou… - Trials, 2024 - Springer
Background The massive scale-up of long-lasting insecticidal nets (LLIN) has led to a major
reduction in malaria burden in many sub-Saharan African (SSA) countries. The World Health …