[HTML][HTML] The legacy of Drosophila imaginal discs
JV Beira, R Paro - Chromosoma, 2016 - Springer
The study of Drosophila imaginal discs has contributed to a number of discoveries in
developmental and cellular biology. In addition to the elucidation of the role of tissue …
developmental and cellular biology. In addition to the elucidation of the role of tissue …
PAX6 in sensory development
V van Heyningen, KA Williamson - Human molecular genetics, 2002 - academic.oup.com
PAX6 function was first identified through aniridia-associated null mutations. Since then, this
transcription factor, with a paired domain and a homeodomain, has become a paradigm …
transcription factor, with a paired domain and a homeodomain, has become a paradigm …
Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions
Life and death fate decisions allow cells to avoid massive apoptotic death in response to
genotoxic stress. Although the regulatory mechanisms and signalling pathways controlling …
genotoxic stress. Although the regulatory mechanisms and signalling pathways controlling …
Specification of the vertebrate eye by a network of eye field transcription factors
ME Zuber, G Gestri, AS Viczian, G Barsacchi… - 2003 - journals.biologists.com
Several eye-field transcription factors (EFTFs) are expressed in the anterior region of the
vertebrate neural plate and are essential for eye formation. The Xenopus EFTFs ET, Rx1 …
vertebrate neural plate and are essential for eye formation. The Xenopus EFTFs ET, Rx1 …
Cnidarians and the evolutionary origin of the nervous system
H Watanabe, T Fujisawa… - Development, growth & …, 2009 - Wiley Online Library
Cnidarians are widely regarded as one of the first organisms in animal evolution possessing
a nervous system. Conventional histological and electrophysiological studies have revealed …
a nervous system. Conventional histological and electrophysiological studies have revealed …
Molecular determinants of retinal ganglion cell development, survival, and regeneration
S Isenmann, A Kretz, A Cellerino - Progress in retinal and eye research, 2003 - Elsevier
The retina is an easily accessible part of the CNS with a well-defined cytological
architecture. It allows for detailed study of the regulation of neurogenesis, determinants of …
architecture. It allows for detailed study of the regulation of neurogenesis, determinants of …
Casting a genetic light on the evolution of eyes
RD Fernald - Science, 2006 - science.org
Light has been exploited for information by organisms through the evolution of
photoreceptors and, ultimately, eyes in animals. Only a handful of eye types exist because …
photoreceptors and, ultimately, eyes in animals. Only a handful of eye types exist because …
R8 development in the Drosophila eye: a paradigm for neural selection and differentiation
BJ Frankfort, G Mardon - 2002 - journals.biologists.com
The Drosophila eye is an outstanding model with which to decipher mechanisms of neural
differentiation. Paramount to normal eye development is the organized selection and …
differentiation. Paramount to normal eye development is the organized selection and …
Sonic hedgehog, secreted by amacrine cells, acts as a short-range signal to direct differentiation and lamination in the zebrafish retina
A Shkumatava, S Fischer, F Müller, U Strahle… - 2004 - journals.biologists.com
Neurogenesis in the zebrafish retina occurs in several waves of differentiation. The first
neurogenic wave generates ganglion cells and depends on hedgehog (hh) signaling …
neurogenic wave generates ganglion cells and depends on hedgehog (hh) signaling …
RNA binding mediates neurotoxicity in the transgenic Drosophila model of TDP-43 proteinopathy
R Ihara, K Matsukawa, Y Nagata… - Human molecular …, 2013 - academic.oup.com
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by
progressive and selective loss of motor neurons. The discovery of mutations in the gene …
progressive and selective loss of motor neurons. The discovery of mutations in the gene …