Gene therapy: Comprehensive overview and therapeutic applications

N Sayed, P Allawadhi, A Khurana, V Singh, U Navik… - Life sciences, 2022 - Elsevier
Gene therapy is the product of man's quest to eliminate diseases. Gene therapy has three
facets namely, gene silencing using siRNA, shRNA and miRNA, gene replacement where …

Cell primitive-based biomimetic functional materials for enhanced cancer therapy

GF Luo, WH Chen, X Zeng, XZ Zhang - Chemical Society Reviews, 2021 - pubs.rsc.org
Cell primitive-based functional materials that combine the advantages of natural substances
and nanotechnology have emerged as attractive therapeutic agents for cancer therapy. Cell …

Sperm-hybrid micromotor for targeted drug delivery

H Xu, M Medina-Sánchez, V Magdanz, L Schwarz… - ACS …, 2018 - ACS Publications
A sperm-driven micromotor is presented as a targeted drug delivery system, which is
appealing to potentially treat diseases in the female reproductive tract. This system is …

Bioengineered and biohybrid bacteria-based systems for drug delivery

Z Hosseinidoust, B Mostaghaci, O Yasa… - Advanced drug delivery …, 2016 - Elsevier
The use of bacterial cells as agents of medical therapy has a long history. Research that was
ignited over a century ago with the accidental infection of cancer patients has matured into a …

Engineering the perfect (bacterial) cancer therapy

NS Forbes - Nature Reviews Cancer, 2010 - nature.com
Bacterial therapies possess many unique mechanisms for treating cancer that are
unachievable with standard methods. Bacteria can specifically target tumours, actively …

Poly (beta-amino ester) s as gene delivery vehicles: challenges and opportunities

J Karlsson, KR Rhodes, JJ Green… - Expert opinion on drug …, 2020 - Taylor & Francis
Introduction Gene delivery technologies are being developed for an increasing number of
biomedical applications, with delivery vehicles including viruses and non-viral materials …

Engineered microbial systems for advanced drug delivery

H Shen, N Aggarwal, KS Wun, YS Lee… - Advanced Drug Delivery …, 2022 - Elsevier
The human body is a natural habitat for a multitude of microorganisms, with bacteria being
the major constituent of the microbiota. These bacteria colonize discrete anatomical …

Bacteria as vectors for gene therapy of cancer

CK Baban, M Cronin, D O'Hanlon… - Bioengineered …, 2010 - Taylor & Francis
Anti-cancer therapy faces major challenges, particularly in terms of specificity of treatment.
The ideal therapy would eradicate tumour cells selectively with minimum side effects on …

Clinical Experience and Recent Advances in the Development of Listeria-Based Tumor Immunotherapies

M Oladejo, Y Paterson, LM Wood - Frontiers in immunology, 2021 - frontiersin.org
The promise of tumor immunotherapy to significantly improve survival in patients who are
refractory to long-standing therapies, such as chemotherapy and radiation, is now being …

[HTML][HTML] Hybrid biomicromotors

L Schwarz, M Medina-Sánchez… - Applied Physics Reviews, 2017 - pubs.aip.org
Micromotors are devices that operate at the microscale and convert energy to motion. Many
micromotors are microswimmers, ie, devices that can move freely in a liquid at a low …