Recent advances in targeted strategies for triple-negative breast cancer

S Zhu, Y Wu, B Song, M Yi, Y Yan, Q Mei… - Journal of Hematology & …, 2023 - Springer
Triple-negative breast cancer (TNBC), a highly aggressive subtype of breast cancer,
negatively expresses estrogen receptor, progesterone receptor, and the human epidermal …

Predictive, preventive, and personalized medicine in breast cancer: targeting the PI3K pathway

M Tufail, JJ Hu, J Liang, CY He, WD Wan… - Journal of Translational …, 2024 - Springer
Breast cancer (BC) is a multifaceted disease characterized by distinct molecular subtypes
and varying responses to treatment. In BC, the phosphatidylinositol 3-kinase (PI3K) pathway …

PIWI-interacting RNA-YBX1 inhibits proliferation and metastasis by the MAPK signaling pathway via YBX1 in triple-negative breast cancer

L Wu, S Huang, W Tian, P Liu, Y Xie, Y Qiu, X Li… - Cell Death …, 2024 - nature.com
Breast cancer is the second leading cause of death in women worldwide, with triple-
negative breast cancer (TNBC) having the worst prognosis. Although there are numerous …

Therapeutic advantage of targeting PRMT5 in combination with chemotherapies or EGFR/HER2 inhibitors in triple-negative breast cancers

R Dakroub, S Huard, Y Hajj-Younes… - … Cancer: Targets and …, 2023 - Taylor & Francis
Purpose Triple-negative breast cancer (TNBC) is the most aggressive breast cancer
subgroup characterized by a high risk of resistance to chemotherapies and high relapse …

Recent advances of multifunctional PLGA nanocarriers in the management of triple-negative breast cancer

YH Dinakar, N Rajana, NU Kumari, V Jain… - AAPS PharmSciTech, 2023 - Springer
Even though chemotherapy stands as a standard option in the therapy of TNBC, problems
associated with it such as anemia, bone marrow suppression, immune suppression, toxic …

[HTML][HTML] Role of Exosomes in Salivary Gland Tumors and Technological Advances in Their Assessment

A Nieszporek, M Wierzbicka, N Labedz, W Zajac… - Cancers, 2024 - mdpi.com
Simple Summary Salivary gland tumors (SGTs) are rare and complex, making them difficult
to diagnose and treat. This work focuses on the role of exosomes, extracellular vesicles …

Recent trends and advances in novel formulations as an armament in Bcl-2/Bax targeted breast cancer

S Samia, PS Chary, O Khan, NK Mehra - International Journal of …, 2024 - Elsevier
Breast cancer (BC) remains a significant health burden worldwide, necessitating the
development of innovative therapeutic strategies. The B-cell lymphoma 2 (Bcl-2) family …

Shikonin blocks CAF-induced TNBC metastasis by suppressing mitochondrial biogenesis through GSK-3β/NEDD4-1 mediated phosphorylation-dependent …

S Fan, X Yan, X Hu, X Liu, S Zhao, Y Zhang… - Journal of Experimental …, 2024 - Springer
Background Triple-negative breast cancer (TNBC) is characterized by its high metastatic
potential, which results in poor patient survival. Cancer-associated fibroblasts (CAFs) are …

[HTML][HTML] Gold Nanobiosensors: Pioneering Breakthroughs in Precision Breast Cancer Detection

S Sadr, A Hajjafari, A Rahdar, S Pandey… - European Journal of …, 2024 - Elsevier
Breast cancer is still one of the major health concerns of today's world. In light of such a
scenario, regular improvement in the detection technique is crucial to meet better early …

PROSPECTIVES OF MIRNA GENE SIGNALLING PATHWAY IN TRIPLE-NEGATIVE BREAST CANCER

K Chakkaravarthi, R Ramesh, T Palaniyandi… - … -Research and Practice, 2023 - Elsevier
Triple-negative breast cancer (TNBC) is one of the destructive breast cancer subtypes which
cannot be treated by current therapies, which is characterized by the lack of estrogen (ER) …