Mechanisms underlying antiarrhythmic properties of cardioprotective agents impacting inflammation and oxidative stress

K Andelova, BS Bacova, M Sykora, P Hlivak… - International Journal of …, 2022 - mdpi.com
The prevention of cardiac life-threatening ventricular fibrillation and stroke-provoking atrial
fibrillation remains a serious global clinical issue, with ongoing need for novel approaches …

Nitrogen, oxygen or sulfur containing heterocyclic compounds as analgesic drugs used as modulators of the nitroxidative stress

K Salat, A Moniczewski… - Mini reviews in medicinal …, 2013 - ingentaconnect.com
Numerous lines of evidence suggest that heterocyclic compounds used as analgesic, anti-
inflammatory and anti-migraine agents can be potent regulators of the nitroxidative stress …

Efficacy of topical atorvastatin‐loaded emulgel and nano‐emulgel 1% on post‐laparotomy pain and wound healing: A randomized double‐blind placebo‐controlled …

F Saghafi, V Ramezani… - International Wound …, 2023 - Wiley Online Library
This study aimed to develop atorvastatin‐loaded emulgel and nano‐emulgel dosage forms
and investigate their efficiency on surgical wound healing and reducing post‐operative pain …

Effects of quercetin and rosuvastatin each alone or in combination on cyclophosphamide-induced premature ovarian failure in female albino mice

MA Elkady, S Shalaby, F Fathi… - Human & …, 2019 - journals.sagepub.com
Background: Cyclophosphamide (CP) causes premature ovarian failure (POF) due to
ovarian toxicity. The toxicity mechanism is attributed to oxidative stress, inflammation, and …

Engineered microencapsulated lactoferrin nanoconjugates for oral targeted treatment of colon cancer

YM Elmorshedy, M Teleb, MA Sallam… - …, 2023 - ACS Publications
Despite current progress in the development of targeted therapies for cancer treatment,
there is a lack in convenient therapeutics for colorectal cancer (CRC). Lactoferrin …

Effect of atorvastatin and methotrexate on solid Ehrlich tumor

AM Kabel, MN Abdel-Rahman, AEDE El-Sisi… - European journal of …, 2013 - Elsevier
Hydroxymethyl glutaryl CoA reductase is the key enzyme in cholesterol synthesis. A
relationship was found between cholesterol and the development of many types of cancer …

Effect of rosuvastatin on non-alcoholic steatohepatitis in patients with metabolic syndrome and hypercholesterolaemia: a preliminary report

K Kargiotis, N Katsiki, VG Athyros… - Current Vascular …, 2014 - ingentaconnect.com
Background: There is no widely accepted treatment for non-alcoholic fatty liver disease
(NAFLD) or its advanced form, non-alcoholic steatohepatitis (NASH). Methods: We …

[PDF][PDF] 急性ST 段抬高型心肌梗死介入治疗前并发心室颤动的预测模型构建

陈红珍, 刘幸娟, 郝琦, 周强, 赵巧燕 - 临床心血管病杂志, 2023 - lcxxgen.whuhzzs.com
目的: 构建急性ST 抬高型心肌梗死并发心室颤动的预测模型. 方法: 回顾性纳入2017 年—2022
年716 例急性ST 段抬高型心肌梗死患者的临床资料, 根据介入治疗前有无心室颤动分成两组 …

Prior statin vs in-hospital statin usage in severe COVID-19: review and meta-analysis

I Alhallak, H Paydak, JL Mehta - Current Problems in Cardiology, 2023 - Elsevier
Studies have shown that statins can decrease COVID-19 mortality in hospitalized patients.
This paper evaluates these studies and reviews the possible mechanism of how statins …

Rosuvastatin attenuates high-salt and cholesterol diet induced neuroinflammation and cognitive impairment via preventing nuclear factor KappaB pathway

I Husain, M Akhtar, D Vohora, MZ Abdin… - Neurochemical …, 2017 - Springer
Recent attention is focused on the impact of diet on health and mental well-being. High-salt
and cholesterol diet (HSCD) is known to be associated with neuroinflammation which is the …