The regulation of hyphae growth in Candida albicans

H Chen, X Zhou, B Ren, L Cheng - Virulence, 2020 - Taylor & Francis
In the last decades, Candida albicans has served as the leading causal agent of life-
threatening invasive infections with mortality rates approaching 40% despite treatment …

Candida albicans cell-type switching and functional plasticity in the mammalian host

SM Noble, BA Gianetti, JN Witchley - Nature Reviews Microbiology, 2017 - nature.com
Candida albicans is a ubiquitous commensal of the mammalian microbiome and the most
prevalent fungal pathogen of humans. A cell-type transition between yeast and hyphal …

Regulatory circuitry governing fungal development, drug resistance, and disease

RS Shapiro, N Robbins, LE Cowen - Microbiology and molecular …, 2011 - Am Soc Microbiol
Pathogenic fungi have become a leading cause of human mortality due to the increasing
frequency of fungal infections in immunocompromised populations and the limited …

Oxidative Stress Responses in the Human Fungal Pathogen, Candida albicans

A da Silva Dantas, A Day, M Ikeh, I Kos, B Achan… - Biomolecules, 2015 - mdpi.com
Candida albicans is a major fungal pathogen of humans, causing approximately 400,000 life-
threatening systemic infections world-wide each year in severely immunocompromised …

Environmental Sensing and Signal Transduction Pathways Regulating Morphopathogenic Determinants of Candida albicans

S Biswas, P Van Dijck, A Datta - Microbiology and molecular …, 2007 - Am Soc Microbiol
Candida albicans is an opportunistic fungal pathogen that is found in the normal
gastrointestinal flora of most healthy humans. However, under certain environmental …

Oxidative stress response pathways in fungi

H Yaakoub, S Mina, A Calenda, JP Bouchara… - Cellular and Molecular …, 2022 - Springer
Fungal response to any stress is intricate, specific, and multilayered, though it employs only
a few evolutionarily conserved regulators. This comes with the assumption that one …

Sensing the environment: lessons from fungi

YS Bahn, C Xue, A Idnurm, JC Rutherford… - Nature Reviews …, 2007 - nature.com
All living organisms use numerous signal-transduction systems to sense and respond to
their environments and thereby survive and proliferate in a range of biological niches …

Candida survival strategies

M Polke, B Hube, ID Jacobsen - Advances in Applied Microbiology, 2015 - Elsevier
Only few Candida species, eg, Candida albicans, Candida glabrata, Candida dubliniensis,
and Candida parapsilosis, are successful colonizers of a human host. Under certain …

Stress adaptation in a pathogenic fungus

AJP Brown, S Budge, D Kaloriti… - Journal of …, 2014 - journals.biologists.com
Candida albicans is a major fungal pathogen of humans. This yeast is carried by many
individuals as a harmless commensal, but when immune defences are perturbed it causes …

Mitogen-activated protein kinase pathways and fungal pathogenesis

X Zhao, R Mehrabi, JR Xu - Eukaryotic cell, 2007 - Am Soc Microbiol
In eukaryotic cells, a family of serine/threonine protein kinases known as mitogen-activated
protein (MAP) kinases (MAPKs) is involved in the transduction of a variety of extracellular …