The regulation of hyphae growth in Candida albicans
In the last decades, Candida albicans has served as the leading causal agent of life-
threatening invasive infections with mortality rates approaching 40% despite treatment …
threatening invasive infections with mortality rates approaching 40% despite treatment …
Candida albicans cell-type switching and functional plasticity in the mammalian host
SM Noble, BA Gianetti, JN Witchley - Nature Reviews Microbiology, 2017 - nature.com
Candida albicans is a ubiquitous commensal of the mammalian microbiome and the most
prevalent fungal pathogen of humans. A cell-type transition between yeast and hyphal …
prevalent fungal pathogen of humans. A cell-type transition between yeast and hyphal …
Regulatory circuitry governing fungal development, drug resistance, and disease
Pathogenic fungi have become a leading cause of human mortality due to the increasing
frequency of fungal infections in immunocompromised populations and the limited …
frequency of fungal infections in immunocompromised populations and the limited …
Oxidative Stress Responses in the Human Fungal Pathogen, Candida albicans
Candida albicans is a major fungal pathogen of humans, causing approximately 400,000 life-
threatening systemic infections world-wide each year in severely immunocompromised …
threatening systemic infections world-wide each year in severely immunocompromised …
Environmental Sensing and Signal Transduction Pathways Regulating Morphopathogenic Determinants of Candida albicans
Candida albicans is an opportunistic fungal pathogen that is found in the normal
gastrointestinal flora of most healthy humans. However, under certain environmental …
gastrointestinal flora of most healthy humans. However, under certain environmental …
Oxidative stress response pathways in fungi
Fungal response to any stress is intricate, specific, and multilayered, though it employs only
a few evolutionarily conserved regulators. This comes with the assumption that one …
a few evolutionarily conserved regulators. This comes with the assumption that one …
Sensing the environment: lessons from fungi
All living organisms use numerous signal-transduction systems to sense and respond to
their environments and thereby survive and proliferate in a range of biological niches …
their environments and thereby survive and proliferate in a range of biological niches …
Candida survival strategies
M Polke, B Hube, ID Jacobsen - Advances in Applied Microbiology, 2015 - Elsevier
Only few Candida species, eg, Candida albicans, Candida glabrata, Candida dubliniensis,
and Candida parapsilosis, are successful colonizers of a human host. Under certain …
and Candida parapsilosis, are successful colonizers of a human host. Under certain …
Stress adaptation in a pathogenic fungus
AJP Brown, S Budge, D Kaloriti… - Journal of …, 2014 - journals.biologists.com
Candida albicans is a major fungal pathogen of humans. This yeast is carried by many
individuals as a harmless commensal, but when immune defences are perturbed it causes …
individuals as a harmless commensal, but when immune defences are perturbed it causes …
Mitogen-activated protein kinase pathways and fungal pathogenesis
In eukaryotic cells, a family of serine/threonine protein kinases known as mitogen-activated
protein (MAP) kinases (MAPKs) is involved in the transduction of a variety of extracellular …
protein (MAP) kinases (MAPKs) is involved in the transduction of a variety of extracellular …