Cancer immunology and immunotherapy are driving forces of research and development in
oncology, mostly focusing on CD8+ T cells and the tumor microenvironment. Recent …

Several immune and immunocompetent cells, including dendritic cells, macrophages,
adipocytes, natural killer cells, T cells, and B cells, are significantly correlated with the …

Angiogenesis, the growth of new blood vessels from preexisting vessels, is associated with
inflammation in various pathological conditions. Well-known angiogenetic factors include …

The critical role of angiogenesis in promoting tumor growth and metastasis is strongly
established. However, tumors show considerable variation in angiogenic characteristics and …

The beneficial roles of probiotics in lowering the gastrointestinal inflammation and
preventing colorectal cancer have been frequently demonstrated, but their …

Cytokines are molecular messengers that allow the cells of the immune system to
communicate with one another to generate a coordinated, robust, but self-limited response …

Solid tumors are not simply clones of cancer cells. Instead, they are abnormal organs
composed of multiple cell types and extracellular matrix. Some aspects of tumor …

Research over the past decade has revealed the increasingly complex biologic features of
the CD4+ T-cell lineage. This T-cell subset, which was originally defined on the basis of …

Immune system acts as a host defensive mechanism protecting against attacking pathogens
and transformed cells, including cancer cells. Th17 cells are a specific subset of T helper …

It has been established that cancer can be promoted and/or exacerbated by inflammation
and infections. Indeed, chronic inflammation orchestrates a tumor-supporting …