Bitter taste-sensing type 2 receptors (TAS2Rs or T2Rs), belonging to the subgroup of family
A G-protein coupled receptors (GPCRs), are of crucial importance in the perception of …

Bitter taste receptors (TAS2Rs or T2Rs) belong to the superfamily of seven-transmembrane
G protein–coupled receptors, which are the targets of> 50% of drugs currently on the market …

The bitterness of foodstuffs is often associated with toxicity, which negatively influences
product acceptability. However, bitter compounds have many benefits, and a slight bitter …

Over the past decade tremendous progress has been made in understanding the functional
role of bitter taste receptors (T2Rs) and bitter taste perception. This review will cover the …

It has recently been shown that taste receptors, in addition to being present in the oral cavity,
exist in various extra-oral organs and tissues such as the thyroid, lungs, skin, stomach …

Heart diseases and related complications constitute a leading cause of death and
socioeconomic threat worldwide. Despite intense efforts and research on the pathogenetic …

Vitamins are known to generate bitterness, which may contribute to an off-taste or aftertaste
for some nutritional supplements. This negative sensation can lead to a reduction in their …

The bitter taste receptor (TAS 2R)‐family of G‐protein‐coupled receptors has been identified
on the tongue as detectors of bitter taste over a decade ago. In the last few years, they have …

The human genome contains∼ 29 bitter taste receptors (T2Rs), which are responsible for
detecting thousands of bitter ligands, including toxic and aversive compounds. This sentinel …

Bitter taste receptors are involved not only in taste perception but in various physiological
functions as their anatomical location is not restricted to the gustatory system. We previously …