Where is nano today and where is it headed? A review of nanomedicine and the dilemma of nanotoxicology
C Domingues, A Santos, C Alvarez-Lorenzo… - ACS …, 2022 - ACS Publications
Worldwide nanotechnology development and application have fueled many scientific
advances, but technophilic expectations and technophobic demands must be …
advances, but technophilic expectations and technophobic demands must be …
The microbiota–gut–brain axis: pathways to better brain health. Perspectives on what we know, what we need to investigate and how to put knowledge into practice
The gut and brain link via various metabolic and signalling pathways, each with the potential
to influence mental, brain and cognitive health. Over the past decade, the involvement of the …
to influence mental, brain and cognitive health. Over the past decade, the involvement of the …
Current state of knowledge on intelligent-response biological and other macromolecular hydrogels in biomedical engineering: A review
M Su, L Ruan, X Dong, S Tian, W Lang, M Wu… - International Journal of …, 2023 - Elsevier
Because intelligent hydrogels have good biocompatibility, a rapid response, and good
degradability as well as a stimulus response mode that is rich, hydrophilic, and similar to the …
degradability as well as a stimulus response mode that is rich, hydrophilic, and similar to the …
[HTML][HTML] The gut–organ-axis concept: Advances the application of gut-on-chip technology
The intestine is considered to be a vital digestive organ to absorb nutrients and is the largest
immune organ, while numerous microorganisms coexist with the host. It is well known that …
immune organ, while numerous microorganisms coexist with the host. It is well known that …
[HTML][HTML] Organs-on-chips technologies–A guide from disease models to opportunities for drug development
Current in-vitro 2D cultures and animal models present severe limitations in recapitulating
human physiopathology with striking discrepancies in estimating drug efficacy and side …
human physiopathology with striking discrepancies in estimating drug efficacy and side …
[HTML][HTML] Organ-on-a-chip meets artificial intelligence in drug evaluation
S Deng, C Li, J Cao, Z Cui, J Du, Z Fu, H Yang… - Theranostics, 2023 - ncbi.nlm.nih.gov
Drug evaluation has always been an important area of research in the pharmaceutical
industry. However, animal welfare protection and other shortcomings of traditional drug …
industry. However, animal welfare protection and other shortcomings of traditional drug …
[HTML][HTML] iPSC-derived organ-on-a-chip models for personalized human genetics and pharmacogenomics studies
VEJM Palasantzas, I Tamargo-Rubio, K Le, J Slager… - Trends in Genetics, 2023 - cell.com
Genome-wide association studies (GWAS) have now correlated hundreds of genetic
variants with complex genetic diseases and drug efficacy. Functional characterization of …
variants with complex genetic diseases and drug efficacy. Functional characterization of …
3D bioprinted organ‐on‐chips
S Rahmani Dabbagh, M Rezapour Sarabi… - …, 2023 - Wiley Online Library
Abstract Organ‐on‐a‐chip (OOC) platforms recapitulate human in vivo‐like conditions more
realistically compared to many animal models and conventional two‐dimensional cell …
realistically compared to many animal models and conventional two‐dimensional cell …
Transendothelial electrical resistance measurement across the blood–brain barrier: a critical review of methods
The blood–brain barrier (BBB) represents the tightest endothelial barrier within the
cardiovascular system characterized by very low ionic permeability. Our aim was to describe …
cardiovascular system characterized by very low ionic permeability. Our aim was to describe …
[HTML][HTML] Dietary lipids from body to brain
EM Emma, J Amanda - Progress in lipid research, 2022 - Elsevier
Dietary habits have drastically changed over the last decades in Western societies. The
Western diet, rich in saturated fatty acids (SFA), trans fatty acids (TFA), omega-6 …
Western diet, rich in saturated fatty acids (SFA), trans fatty acids (TFA), omega-6 …