T lymphocytes play a key role in immunity by distinguishing self from nonself peptide
antigens and regulating both the cellular and humoral arms of the immune system. Acquired …

In addition to marshalling immune and inflammatory responses, transcription factors of the
NF-κB family control cell survival. This control is crucial to a wide range of biological …

Members of the soil‐dwelling prokaryotic genus Streptomyces produce many secondary
metabolites, including antibiotics and anti‐tumour agents. Their formation is coupled with the …

The book aims to provide an introduction to mathematical models that describe the
dynamics of tumor growth and the evolution of tumor cells. It can be used as a textbook for …

Exposure of mammalian cells to oxidant stress causes early (iron catalysed) lysosomal
rupture followed by apoptosis or necrosis. Enhanced intracellular production of reactive …

The book shows how mathematical and computational models can be used to study cancer
biology. It introduces the concept of mathematical modeling and then applies it to a variety of …

Galectins have emerged as a novel family of immunoregulatory proteins implicated in T cell
homeostasis. Recent studies showed that galectin-1 (Gal-1) plays a key role in tumor …

Resistance towards apoptosis is a key factor for the survival of a malignant cell. Cancer
results if there is too little apoptosis and cells grow faster and live longer than normal cells. In …

Programmed cell death (PCD) is a genetically determined process of cellular suicide that is
activated in response to cellular stress or damage, as well as in response to the …

Purpose To investigate the effect of training status on lymphocyte apoptosis as well as the
expression of cell death receptors and ligands after a marathon run, and to compare these …