Tissue resident memory T cells (TRM) are a critical component of the immune system,
providing the body with an immediate and highly specific response against pathogens re …

Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease. The disease is
characterized by activation and dysregulation of both the innate and the adaptive immune …

An abnormal neutrophil subset has been identified in the PBMC fractions from lupus
patients. We have proposed that these low-density granulocytes (LDGs) play an important …

Background: The IL-17 (interleukin 17) family consists of six structurally related pro-
inflammatory cytokines, namely IL-17A to IL-17F. These cytokines have garnered significant …

Despite the success of targeted therapies in managing immune-mediated inflammatory
diseases (IMIDs) such as RA, IBDs, MS and psoriasis, unmet needs for such approach in …

Ro52 is a common target of circulating autoantibodies in autoimmune disease. Data indicate
that anti-Ro52 antibodies are associated with distinct clinical manifestations. It is therefore of …

The antimicrobial peptides (AMP) psoriasin (S100A7) and koebnerisin (S100A15) are
differently induced in psoriatic skin. They act synergistically as chemoattractants and …

Systemic lupus erythematosus (SLE) is a multifactorial autoimmune disease which can affect
various tissues and organs, posing significant challenges for clinical diagnosis and …

Genetic factors exert an important role in determining Systemic Lupus Erythematosus (SLE)
susceptibility, interplaying with environmental factors. Several genetic studies in various SLE …

The pathophysiology of cutaneous lupus erythematosus (CLE) encompasses the complex
interactions between genetics, the environment, and cells and their products. Recent data …