One of the major impediments to drug development is low aqueous solubility and thus poor
bioavailability, which leads to insufficient clinical utility. Around 70–80% of drugs in the …

Artificial tears are the mainstay of dry eye disease management, but also have a role in
corneal abrasion and wound healing, pain and inflammation management, conjunctivitis …

The most common route of administration of ophthalmic drugs is the topical route because it
is convenient, non-invasive, and accessible to all patients. Unfortunately, drugs …

Ocular trauma or other ocular conditions can be significantly debilitating in space. A
literature review of over 100 articles and NASA evidence books, queried for eye related …

Dry eye disease (DED) is a multifactorial disease of the ocular surface that may be
accompanied by discomfort and visual disturbances to a level that reduces quality of life …

The NASA human system risk board (HSRB) has long focused on trauma and acute medical
illness as a key contributor to high level in-flight medical risk. However, ocular issues …

Although the ultimate goal of dry eye disease (DED) management is to restore the ocular
surface and tear film homeostasis and address any accompanying symptoms, addressing …

Purpose. Dry eye disease (DED) can be triggered using preserved ophthalmic formulations
or prostaglandin analogs. In this prospective, nonrandomized, open‐label pilot study, we …

Background: Currently, hyaluronic acid (HA) and carboxymethyl cellulose sodium (CMC) are
common polymers incorporated in artificial tears (ATs). The aim of the present study was to …

Dry eye disease (DED) is a common multifactorial disease affecting a substantial proportion
of the population worldwide. Objective tests and subjective symptoms evaluation are …