Polymer‐based mRNA delivery strategies for advanced therapies

W Yang, L Mixich, E Boonstra… - Advanced Healthcare …, 2023 - Wiley Online Library
Messenger RNA (mRNA)‐based therapies offer great promise for the treatment of a variety
of diseases. In 2020, two FDA approvals of mRNA‐based vaccines have elevated mRNA …

Smart and bioinspired systems for overcoming biological barriers and enhancing disease theranostics

X Li, Y Gao, H Li, JP Majoral, X Shi, A Pich - Progress in Materials Science, 2023 - Elsevier
Nanomedicine has emerged as a promising mean to improve theranostic efficacy and
reduce side effects. Currently, only very small percentage of injected dose reaches the solid …

Gold-nanoparticle-assisted plasmonic photothermal therapy advances toward clinical application

MRK Ali, Y Wu, MA El-Sayed - The Journal of Physical Chemistry …, 2019 - ACS Publications
Plasmonic photothermal therapy (PPTT), a type of treatment involving the intravenous or
intratumoral injection to introduce gold nanoparticles to cancerous cells and the subsequent …

Nanodrug delivery: is the enhanced permeability and retention effect sufficient for curing cancer?

Y Nakamura, A Mochida, PL Choyke… - Bioconjugate …, 2016 - ACS Publications
Nanotechnology offers several attractive design features that have prompted its exploration
for cancer diagnosis and treatment. Nanosized drugs have a large loading capacity, the …

[HTML][HTML] Challenges and strategies in anti-cancer nanomedicine development: An industry perspective

JI Hare, T Lammers, MB Ashford, S Puri, G Storm… - Advanced drug delivery …, 2017 - Elsevier
Successfully translating anti-cancer nanomedicines from pre-clinical proof of concept to
demonstration of therapeutic value in the clinic is challenging. Having made significant …

Ligand‐installed nanocarriers toward precision therapy

P Mi, H Cabral, K Kataoka - Advanced Materials, 2020 - Wiley Online Library
Abstract Development of drug‐delivery systems that selectively target neoplastic cells has
been a major goal of nanomedicine. One major strategy for achieving this milestone is to …

Mechanisms and biomaterials in pH-responsive tumour targeted drug delivery: a review

M Kanamala, WR Wilson, M Yang, BD Palmer, Z Wu - Biomaterials, 2016 - Elsevier
As the mainstay in the treatment of various cancers, chemotherapy plays a vital role, but still
faces many challenges, such as poor tumour selectivity and multidrug resistance (MDR) …

pH-sensitive biomaterials for drug delivery

S Zhuo, F Zhang, J Yu, X Zhang, G Yang, X Liu - Molecules, 2020 - mdpi.com
The development of precise and personalized medicine requires novel formulation
strategies to deliver the therapeutic payloads to the pathological tissues, producing …

Nanomedicine for tumor microenvironment modulation and cancer treatment enhancement

J Liu, Q Chen, L Feng, Z Liu - Nano Today, 2018 - Elsevier
Cancer, one of major threats to the human health, possesses intricate structure and
constituents distinctive from normal organs and tissues. It has been well recognized that the …

[HTML][HTML] Nanotechnology advances in the detection and treatment of cancer: an overview

S Mosleh-Shirazi, M Abbasi, M reza Moaddeli… - …, 2022 - ncbi.nlm.nih.gov
Over the last few years, progress has been made across the nanomedicine landscape, in
particular, the invention of contemporary nanostructures for cancer diagnosis and …