Nanotechnology in healthcare, and its safety and environmental risks

X Ma, Y Tian, R Yang, H Wang, LW Allahou… - Journal of …, 2024 - Springer
Nanotechnology holds immense promise in revolutionising healthcare, offering
unprecedented opportunities in diagnostics, drug delivery, cancer therapy, and combating …

Gold nanoparticles in neurological diseases: A review of neuroprotection

MC Chiang, YP Yang, CJB Nicol, CJ Wang - International Journal of …, 2024 - mdpi.com
This review explores the diverse applications of gold nanoparticles (AuNPs) in neurological
diseases, with a specific focus on Alzheimer's disease (AD), Parkinson's disease (PD), and …

[HTML][HTML] The piper at the gates of brain: A systematic review of surface modification strategies on lipid nanoparticles to overcome the Blood-Brain-Barrier

R Vargas, C Lizano-Barrantes, M Romero… - International Journal of …, 2024 - Elsevier
Abstract The Blood-Brain Barrier (BBB) significantly impedes drug delivery to the central
nervous system. Nanotechnology, especially surface-functionalized lipid nanoparticles …

Enhanced Cellular Uptake and Transport of Bovine lactoferrin using pectin-and Chitosan-modified solid lipid nanoparticles

X Yao, C Bunt, M Liu, SY Quek, J Shaw, J Cornish… - Pharmaceutics, 2023 - mdpi.com
Aim: The aim of this project is to use pectin-and chitosan-modified solid lipid nanoparticles
for bovine lactoferrin to enhance its cellular uptake and transport. Methods: Solid lipid …

Mitochondria-targeting Cu2-xSe-TPP with dual enzyme activity alleviates Alzheimer's disease by modulating oxidative stress

L Wang, X Yuan, Q Cai, Y Chen, Z Jia, Q Mai… - Colloids and Surfaces B …, 2025 - Elsevier
Mitochondrial dysfunction in microglia has been implicated as a key pathogenesis of most
neurodegenerative diseases including Alzheimer's disease (AD). Abnormal production of …

Transforming brain cancer therapeutics: unlocking the power of blood-brain barrier-targeting strategies for superior treatment outcomes and precision medicine

A Viswanathan, N Brahma - Neurosurgical Review, 2024 - Springer
The treatment of brain tumors is significantly hindered by the Blood-Brain Barrier (BBB), a
selective barrier that restricts the passage of therapeutic agents to the brain. Recent …

Form Equals Function: Influence of Coacervate Architecture on Drug Delivery Applications

C Lim, WC Blocher McTigue - ACS Biomaterials Science & …, 2024 - ACS Publications
Complex coacervates, formed through electrostatic interactions between oppositely charged
polymers, present a versatile platform for drug delivery, providing rapid assembly, selective …

[HTML][HTML] In vitro and in vivo toxicity of thiolated and PEGylated organosilica nanoparticles

BA Zhaisanbayeva, EA Mun, L Ulmanova… - International Journal of …, 2024 - Elsevier
This study comprises the comprehensive toxicological assessment of thiolated organosilica
nanoparticles (NPs) synthesised from 3-mercaptopropyltrimethoxysilane (MPTS). We …

Aging, ROS, and cellular senescence: a trilogy in the progression of liver fibrosis

WH Almalki, SS Almujri - Biogerontology, 2025 - Springer
Ageing is an inevitable and multifaceted biological process that impacts a wide range of
cellular and molecular mechanisms, leading to the development of various diseases, such …

Nanoparticle-Mediated L-Carnitine Delivery for Improved Male Fertility

AM Moghadam, MJ Javid-Naderi, S Fathi-karkan… - Journal of Drug Delivery …, 2024 - Elsevier
Male infertility, affecting more than 40% of couples experiencing difficulties in conception, is
a significant worldwide health issue. L-Carnitine (LC) has emerged as a potential …